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Structure-based development of novel substrate-type G9a inhibitors as epigenetic modulators for sickle cell disease treatment.
Nishigaya Y, Takase S, Sumiya T, Sato T, Niwa H, Sato S, Nakata A, Matsuoka S, Maemoto Y, Hashimoto N, Namie R, Honma T, Umehara T, Shirouzu M, Koyama H, Yoshida M, Ito A, Shirai F. Nishigaya Y, et al. Among authors: shirouzu m. Bioorg Med Chem Lett. 2024 Sep 15;110:129856. doi: 10.1016/j.bmcl.2024.129856. Epub 2024 Jun 22. Bioorg Med Chem Lett. 2024. PMID: 38914346
Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S, Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K, Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki S, Suzuki T, Suzuki T. Zhao X, et al. Among authors: shirouzu m. Cell. 2023 Dec 7;186(25):5517-5535.e24. doi: 10.1016/j.cell.2023.10.026. Epub 2023 Nov 21. Cell. 2023. PMID: 37992713 Free article.
445 results