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Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models.
Jiménez de Oya N, Esler WP, Huard K, El-Kattan AF, Karamanlidis G, Blázquez AB, Ramos-Ibeas P, Escribano-Romero E, Louloudes-Lázaro A, Casas J, Sobrino F, Hoehn K, James DE, Gutiérrez-Adán A, Saiz JC, Martín-Acebes MA. Jiménez de Oya N, et al. Among authors: el kattan af. Emerg Microbes Infect. 2019;8(1):624-636. doi: 10.1080/22221751.2019.1604084. Emerg Microbes Infect. 2019. PMID: 30999821 Free PMC article.
2-Aminopyridine-Based Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Inhibitors: Assessment of Mechanism-Based Safety.
Dow RL, Ammirati M, Bagley SW, Bhattacharya SK, Buckbinder L, Cortes C, El-Kattan AF, Ford K, Freeman GB, Guimarães CRW, Liu S, Niosi M, Skoura A, Tess D. Dow RL, et al. Among authors: el kattan af. J Med Chem. 2018 Apr 12;61(7):3114-3125. doi: 10.1021/acs.jmedchem.8b00152. Epub 2018 Apr 3. J Med Chem. 2018. PMID: 29570292
Highlights From the American Association of Pharmaceutical Scientists/ International Transporter Consortium Joint Workshop on Drug Transporters in Absorption, Distribution, Metabolism, and Excretion: From the Bench to the Bedside - Clinical Pharmacology Considerations.
Ronaldson PT, Bauer B, El-Kattan AF, Shen H, Salphati L, Louie SW. Ronaldson PT, et al. Among authors: el kattan af. Clin Pharmacol Ther. 2016 Nov;100(5):419-422. doi: 10.1002/cpt.439. Epub 2016 Sep 13. Clin Pharmacol Ther. 2016. PMID: 27500791 Free PMC article.
32 results