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PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity.
Djajawi TM, Pijpers L, Srivaths A, Chisanga D, Chan KF, Hogg SJ, Neil L, Rivera SM, Bartonicek N, Ellis SL, Lim Kam Sian TCC, Faridi P, Liao Y, Pal B, Behren A, Shi W, Vervoort SJ, Johnstone RW, Kearney CJ. Djajawi TM, et al. Among authors: behren a. Cell Rep. 2024 Mar 26;43(3):113831. doi: 10.1016/j.celrep.2024.113831. Epub 2024 Feb 23. Cell Rep. 2024. PMID: 38401121 Free article.
T cell factor 1 (TCF-1) defines T cell differentiation in colorectal cancer.
Tran K, Kumari AN, Raghu D, Cox DRA, Goh SK, Perini MV, Muralidharan V, Tebbutt NC, Behren A, Mariadason J, Williams DS, Mielke LA. Tran K, et al. Among authors: behren a. iScience. 2024 Aug 22;27(9):110754. doi: 10.1016/j.isci.2024.110754. eCollection 2024 Sep 20. iScience. 2024. PMID: 39280606 Free PMC article.
Vγ9Vδ2 T cells recognize butyrophilin 2A1 and 3A1 heteromers.
Fulford TS, Soliman C, Castle RG, Rigau M, Ruan Z, Dolezal O, Seneviratna R, Brown HG, Hanssen E, Hammet A, Li S, Redmond SJ, Chung A, Gorman MA, Parker MW, Patel O, Peat TS, Newman J, Behren A, Gherardin NA, Godfrey DI, Uldrich AP. Fulford TS, et al. Among authors: behren a. Nat Immunol. 2024 Aug;25(8):1355-1366. doi: 10.1038/s41590-024-01892-z. Epub 2024 Jul 16. Nat Immunol. 2024. PMID: 39014161
A gut microbial signature for combination immune checkpoint blockade across cancer types.
Gunjur A, Shao Y, Rozday T, Klein O, Mu A, Haak BW, Markman B, Kee D, Carlino MS, Underhill C, Frentzas S, Michael M, Gao B, Palmer J, Cebon J, Behren A, Adams DJ, Lawley TD. Gunjur A, et al. Among authors: behren a. Nat Med. 2024 Mar;30(3):797-809. doi: 10.1038/s41591-024-02823-z. Epub 2024 Mar 1. Nat Med. 2024. PMID: 38429524 Free PMC article.
TCF-1 limits intraepithelial lymphocyte antitumor immunity in colorectal carcinoma.
Yakou MH, Ghilas S, Tran K, Liao Y, Afshar-Sterle S, Kumari A, Schmid K, Dijkstra C, Inguanti C, Ostrouska S, Wilcox J, Smith M, Parathan P, Allam A, Xue HH, Belz GT, Mariadason JM, Behren A, Drummond GR, Ruscher R, Williams DS, Pal B, Shi W, Ernst M, Raghu D, Mielke LA. Yakou MH, et al. Among authors: behren a. Sci Immunol. 2023 Oct 13;8(88):eadf2163. doi: 10.1126/sciimmunol.adf2163. Epub 2023 Oct 6. Sci Immunol. 2023. PMID: 37801516
Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.
Rodriguez-Martin B, Alvarez EG, Baez-Ortega A, Zamora J, Supek F, Demeulemeester J, Santamarina M, Ju YS, Temes J, Garcia-Souto D, Detering H, Li Y, Rodriguez-Castro J, Dueso-Barroso A, Bruzos AL, Dentro SC, Blanco MG, Contino G, Ardeljan D, Tojo M, Roberts ND, Zumalave S, Edwards PA, Weischenfeldt J, Puiggròs M, Chong Z, Chen K, Lee EA, Wala JA, Raine KM, Butler A, Waszak SM, Navarro FCP, Schumacher SE, Monlong J, Maura F, Bolli N, Bourque G, Gerstein M, Park PJ, Wedge DC, Beroukhim R, Torrents D, Korbel JO, Martincorena I, Fitzgerald RC, Van Loo P, Kazazian HH, Burns KH; PCAWG Structural Variation Working Group; Campbell PJ, Tubio JMC; PCAWG Consortium. Rodriguez-Martin B, et al. Nat Genet. 2023 Jun;55(6):1080. doi: 10.1038/s41588-023-01319-9. Nat Genet. 2023. PMID: 36944736 Free PMC article. No abstract available.
127 results