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471 results

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Fluoropyrimidine type, patient age, tumour sidedness and mutation status as determinants of benefit in patients with metastatic colorectal cancer treated with EGFR monoclonal antibodies: individual patient data pooled analysis of randomised trials from the ARCAD database.
Karapetis CS, Liu H, Sorich MJ, Pederson LD, Van Cutsem E, Maughan T, Douillard JY, O'Callaghan CJ, Jonker D, Bokemeyer C, Sobrero A, Cremolini C, Chibaudel B, Zalcberg J, Adams R, Buyse M, Peeters M, Yoshino T, de Gramont A, Shi Q. Karapetis CS, et al. Among authors: buyse m. Br J Cancer. 2024 May;130(8):1269-1278. doi: 10.1038/s41416-024-02604-y. Epub 2024 Feb 24. Br J Cancer. 2024. PMID: 38402342 Free PMC article. Clinical Trial.
Refining Risk Stratification of High-risk and Locoregional Prostate Cancer: A Pooled Analysis of Randomized Trials.
Ravi P, Xie W, Buyse M, Halabi S, Kantoff PW, Sartor O, Attard G, Clarke N, D'Amico A, Dignam J, James N, Fizazi K, Gillessen S, Parulekar W, Sandler H, Spratt DE, Sydes MR, Tombal B, Williams S, Sweeney CJ. Ravi P, et al. Among authors: buyse m. Eur Urol. 2024 May 21:S0302-2838(24)02380-7. doi: 10.1016/j.eururo.2024.04.038. Online ahead of print. Eur Urol. 2024. PMID: 38777647
Minimization in randomized clinical trials.
Coart E, Bamps P, Quinaux E, Sturbois G, Saad ED, Burzykowski T, Buyse M. Coart E, et al. Among authors: buyse m. Stat Med. 2023 Dec 10;42(28):5285-5311. doi: 10.1002/sim.9916. Epub 2023 Oct 23. Stat Med. 2023. PMID: 37867447
Validation of metastasis-free survival as a surrogate endpoint for overall survival in localized prostate cancer in the era of docetaxel for castration-resistant prostate cancer.
Xie W, Ravi P, Buyse M, Halabi S, Kantoff P, Sartor O, Soule H, Clarke N, Dignam J, James N, Fizazi K, Gillessen S, Mottet N, Murphy L, Parulekar W, Sandler H, Tombal B, Williams S, Sweeney CJ. Xie W, et al. Among authors: buyse m. Ann Oncol. 2024 Mar;35(3):285-292. doi: 10.1016/j.annonc.2023.11.017. Epub 2023 Dec 5. Ann Oncol. 2024. PMID: 38061427
Challenges and Opportunities in Establishing Appropriate Intermediate Endpoints Reflecting Patient Benefit: A Roadmap for Research and Clinical Application in Nonmetastatic Prostate Cancer.
Brookman-May SD, Buyse M, Freedland SJ, Miladinovic B, Zhang K, Fendler WP, Feng F, Sartor O, Sweeney CJ. Brookman-May SD, et al. Among authors: buyse m. Eur Urol. 2024 Aug;86(2):81-87. doi: 10.1016/j.eururo.2024.04.024. Epub 2024 May 18. Eur Urol. 2024. PMID: 38762392
Restricted Net Treatment Benefit in oncology.
Piffoux M, Ozenne B, De Backer M, Buyse M, Chiem JC, Péron J. Piffoux M, et al. Among authors: buyse m. J Clin Epidemiol. 2024 Jun;170:111340. doi: 10.1016/j.jclinepi.2024.111340. Epub 2024 Apr 1. J Clin Epidemiol. 2024. PMID: 38570079 Free article.
Benefit of Avasopasem Manganese on Severe Oral Mucositis in Head and Neck Cancer in the ROMAN Trial: Unplanned Secondary Analysis.
Anderson C, Salvaggio S, De Backer M, Chiem JC, Walker G, Saunders D, Lee CM, Dunlap N, Kennedy E, Beardsley R, Schoen B, Buyse M. Anderson C, et al. Among authors: buyse m. Adv Radiat Oncol. 2024 Nov 9;10(1):101674. doi: 10.1016/j.adro.2024.101674. eCollection 2025 Jan. Adv Radiat Oncol. 2024. PMID: 39678920 Free PMC article.
The tyranny of non-inferiority trials.
Tannock IF, Buyse M, De Backer M, Earl H, Goldstein DA, Ratain MJ, Saltz LB, Sonke GS, Strohbehn GW. Tannock IF, et al. Among authors: buyse m. Lancet Oncol. 2024 Oct;25(10):e520-e525. doi: 10.1016/S1470-2045(24)00218-3. Lancet Oncol. 2024. PMID: 39362263 Review.
Trial Design for Cancer Immunotherapy: A Methodological Toolkit.
Saad ED, Coart E, Deltuvaite-Thomas V, Garcia-Barrado L, Burzykowski T, Buyse M. Saad ED, et al. Among authors: buyse m. Cancers (Basel). 2023 Sep 21;15(18):4669. doi: 10.3390/cancers15184669. Cancers (Basel). 2023. PMID: 37760636 Free PMC article. Review.
471 results