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Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors.
Giacomini G, Piquet S, Chevallier O, Dabin J, Bai SK, Kim B, Siddaway R, Raught B, Coyaud E, Shan CM, Reid RJD, Toda T, Rothstein R, Barra V, Wilhelm T, Hamadat S, Bertin C, Crane A, Dubois F, Forne I, Imhof A, Bandopadhayay P, Beroukhim R, Naim V, Jia S, Hawkins C, Rondinelli B, Polo SE. Giacomini G, et al. Among authors: imhof a. Nucleic Acids Res. 2024 Mar 21;52(5):2372-2388. doi: 10.1093/nar/gkad1257. Nucleic Acids Res. 2024. PMID: 38214234 Free PMC article.
Epigenetic dosage identifies two major and functionally distinct β cell subtypes.
Dror E, Fagnocchi L, Wegert V, Apostle S, Grimaldi B, Gruber T, Panzeri I, Heyne S, Höffler KD, Kreiner V, Ching R, Tsai-Hsiu Lu T, Semwal A, Johnson B, Senapati P, Lempradl A, Schones D, Imhof A, Shen H, Pospisilik JA. Dror E, et al. Among authors: imhof a. Cell Metab. 2023 May 2;35(5):821-836.e7. doi: 10.1016/j.cmet.2023.03.008. Epub 2023 Mar 21. Cell Metab. 2023. PMID: 36948185 Free PMC article.
Myeloid cells coordinately induce glioma cell-intrinsic and cell-extrinsic pathways for chemoresistance via GP130 signaling.
Cheng J, Li M, Motta E, Barci D, Song W, Zhou D, Li G, Zhu S, Yang A, Vaillant BD, Imhof A, Forné I, Spiegl-Kreinecker S, Zhang N, Katayama H, Bhat KPL, Flüh C, Kälin RE, Glass R. Cheng J, et al. Among authors: imhof a. Cell Rep Med. 2024 Aug 20;5(8):101658. doi: 10.1016/j.xcrm.2024.101658. Epub 2024 Jul 24. Cell Rep Med. 2024. PMID: 39053460 Free PMC article.
521 results