Chen P - Search Results

1

Discovery of novel osthole derivatives exerting anti-inflammatory effect on DSS-induced ulcerative colitis and LPS-induced acute lung injury in mice.

Zhou Y, Du Z, Wu Q, Guo M, Chen Z, Sun C, Li X, Zou Y, Zheng Z, Chen P, Cho WJ, Cho YC, Chattipakorn N, Wang Y, Liang G, Tang Q. Zhou Y, et al. Among authors: chen z, chen p. Eur J Med Chem. 2024 Mar 15;268:116252. doi: 10.1016/j.ejmech.2024.116252. Epub 2024 Feb 22. Eur J Med Chem. 2024. PMID: 38422703

2

Design, synthesis and bioactivity evaluation of fisetin derivatives as potential anti-inflammatory agents against LPS-induced acute lung injury.

Wang X, Yang J, Ding B, Chen P, Xu Z, Zhao Y, Chen P, Chattipakorn N, Liang G, Wu D, Tang Q. Wang X, et al. Among authors: chen p. Bioorg Med Chem. 2021 Nov 1;49:116456. doi: 10.1016/j.bmc.2021.116456. Epub 2021 Oct 5. Bioorg Med Chem. 2021. PMID: 34628233

3

Design, synthesis and anticancer evaluation of 6,7-disubstituted-4-phenoxyquinoline derivatives bearing 1,8-naphthyridine-3-carboxamide moiety as novel multi-target TKIs.

Chen P, Zhao Y, Zhang J, Duan Y, Dai J, He J, Wang X, Chen X, Chen P, Zhao W, Wang X, Zhuang Z, Yang D, Liang G, Tang Q. Chen P, et al. Among authors: chen x. Bioorg Chem. 2022 Apr;121:105672. doi: 10.1016/j.bioorg.2022.105672. Epub 2022 Feb 18. Bioorg Chem. 2022. PMID: 35202851

4

Costunolide alleviates atherosclerosis in high-fat diet-fed ApoE^-/- mice through covalently binding to IKKβ and inhibiting NF-κB-mediated inflammation.

Huang ZQ, Luo W, Li WX, Chen P, Wang Z, Chen RJ, Wang Y, Huang WJ, Liang G. Huang ZQ, et al. Among authors: chen p, chen rj. Acta Pharmacol Sin. 2023 Jan;44(1):58-70. doi: 10.1038/s41401-022-00928-0. Epub 2022 Jun 16. Acta Pharmacol Sin. 2023. PMID: 35710877 Free PMC article.

5

Design, synthesis, and bioactivity evaluation of novel 1-(4-(benzylsulfonyl)-2-nitrophenyl) derivatives as potential anti-inflammatory agents against LPS-induced acute lung injury.

Chen P, Yu Y, Su S, Du Z, Cai B, Sun X, Chattipakorn N, Samorodov AV, Pavlov VN, Tang Q, Cho WJ, Liang G. Chen P, et al. Bioorg Med Chem Lett. 2023 Jan 15;80:129097. doi: 10.1016/j.bmcl.2022.129097. Epub 2022 Dec 1. Bioorg Med Chem Lett. 2023. PMID: 36462751

6

Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis.

Yang J, Wang M, Xu Y, Liao J, Li X, Zhou Y, Dai J, Li X, Chen P, Chen G, Cho WJ, Chattipakorn N, Samorodov AV, Pavlov VN, Wang Y, Liang G, Tang Q. Yang J, et al. Among authors: chen p, chen g. Eur J Med Chem. 2023 Mar 5;249:115144. doi: 10.1016/j.ejmech.2023.115144. Epub 2023 Jan 23. Eur J Med Chem. 2023. PMID: 36708679

7

Novel O-benzylcinnamic acid derivative L26 treats acute lung injury in mice by MD-2.

Li X, Yin L, Liao J, Yang J, Cai B, Yu Y, Su S, Du Z, Li X, Zhou Y, Chen P, Cho WJ, Chattipakorn N, Samorodov AV, Pavlov VN, Zhang F, Liang G, Tang Q. Li X, et al. Among authors: chen p. Eur J Med Chem. 2023 Apr 5;252:115289. doi: 10.1016/j.ejmech.2023.115289. Epub 2023 Mar 17. Eur J Med Chem. 2023. PMID: 36963290

8

Design and synthesis optimization of novel diimide indoles derivatives for ameliorating acute lung injury through modulation of NF-κB signaling pathway.

Zheng Z, Li X, Chen P, Zou Y, Shi X, Li X, Young Kim E, Liao J, Yang J, Chattipakorn N, Wu G, Tang Q, Cho WJ, Liang G. Zheng Z, et al. Among authors: chen p. Bioorg Chem. 2023 Jul;136:106557. doi: 10.1016/j.bioorg.2023.106557. Epub 2023 Apr 21. Bioorg Chem. 2023. PMID: 37121106

9

Design, Synthesis, and Bioevaluation of Novel MyD88 Inhibitor c17 against Acute Lung Injury Derived from the Virtual Screen.

Chen P, Zhou Y, Li X, Yang J, Zheng Z, Zou Y, Li X, Liao J, Dai J, Xu Y, Yin L, Chen G, Gu J, Ouyang Q, Cho WJ, Tang Q, Liang G. Chen P, et al. Among authors: chen g. J Med Chem. 2023 May 25;66(10):6938-6958. doi: 10.1021/acs.jmedchem.3c00359. Epub 2023 May 2. J Med Chem. 2023. PMID: 37130331

10

Design, synthesis, and bioactivity evaluation of novel amide/sulfonamide derivatives as potential anti-inflammatory agents against acute lung injury and ulcerative colitis.

Chen P, Yang J, Zhou Y, Li X, Zou Y, Zheng Z, Guo M, Chen Z, Cho WJ, Chattipakorn N, Wu W, Tang Q, Liang G. Chen P, et al. Among authors: chen z. Eur J Med Chem. 2023 Nov 5;259:115706. doi: 10.1016/j.ejmech.2023.115706. Epub 2023 Aug 2. Eur J Med Chem. 2023. PMID: 37572538

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