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PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons.
Milioto C, Carcolé M, Giblin A, Coneys R, Attrebi O, Ahmed M, Harris SS, Lee BI, Yang M, Ellingford RA, Nirujogi RS, Biggs D, Salomonsson S, Zanovello M, de Oliveira P, Katona E, Glaria I, Mikheenko A, Geary B, Udine E, Vaizoglu D, Anoar S, Jotangiya K, Crowley G, Smeeth DM, Adams ML, Niccoli T, Rademakers R, van Blitterswijk M, Devoy A, Hong S, Partridge L, Coyne AN, Fratta P, Alessi DR, Davies B, Busche MA, Greensmith L, Fisher EMC, Isaacs AM. Milioto C, et al. Among authors: giblin a. Nat Neurosci. 2024 Apr;27(4):643-655. doi: 10.1038/s41593-024-01589-4. Epub 2024 Feb 29. Nat Neurosci. 2024. PMID: 38424324 Free PMC article.
A monocarboxylate transporter rescues frontotemporal dementia and Alzheimer's disease models.
Xu D, Vincent A, González-Gutiérrez A, Aleyakpo B, Anoar S, Giblin A, Atilano ML, Adams M, Shen D, Thoeng A, Tsintzas E, Maeland M, Isaacs AM, Sierralta J, Niccoli T. Xu D, et al. Among authors: giblin a. PLoS Genet. 2023 Sep 21;19(9):e1010893. doi: 10.1371/journal.pgen.1010893. eCollection 2023 Sep. PLoS Genet. 2023. PMID: 37733679 Free PMC article.
The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4.
Feringa FM, Hertog SJK, Wang L, Derks RJE, Kruijff I, Erlebach L, Heijneman J, Miramontes R, Pömpner N, Blomberg N, Olivier-Jimenez D, Johansen LE, Cammack AJ, Giblin A, Toomey CE, Rose IVL, Yuan H, Ward M, Isaacs AM, Kampmann M, Kronenberg-Versteeg D, Lashley T, Thompson LM, Ori A, Mohammed Y, Giera M, van der Kant R. Feringa FM, et al. Among authors: giblin a. bioRxiv [Preprint]. 2024 Jul 3:2024.07.01.601474. doi: 10.1101/2024.07.01.601474. bioRxiv. 2024. PMID: 39005258 Free PMC article. Preprint.
Targeted protein degradation of PDE4 shortforms by a novel proteolysis targeting chimera.
Sin YY, Giblin A, Judina A, Rujirachaivej P, Corral LG, Glennon E, Tai ZX, Feng T, Torres E, Zorn A, Gorelik J, Kyurkchieva E, Yenchitsomanus PT, Swindlehurst C, Chan K, Stirling D, Baillie GS. Sin YY, et al. Among authors: giblin a. FEBS J. 2024 Dec 13. doi: 10.1111/febs.17359. Online ahead of print. FEBS J. 2024. PMID: 39673076
A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
NIHR Global Health Research Unit on Global Surgery; STARSurg Collaborative. NIHR Global Health Research Unit on Global Surgery, et al. Lancet Digit Health. 2024 Jul;6(7):e507-e519. doi: 10.1016/S2589-7500(24)00065-7. Lancet Digit Health. 2024. PMID: 38906616 Free article.
Consensus on managing open ankle fractures in the frail patient.
Guryel E, McEwan J, Qureshi AA, Robertson A, Ahluwalia R; Open Ankle Fracture of the Frail (OAFF) Collaborative Group; OAFF Collaborative Group; Baxter M, Mason L, Eardley W, McFadyen I, Trompeter A, Giblin AV, Handley B, Lahoti O. Guryel E, et al. Among authors: giblin av. Bone Jt Open. 2024 Mar 22;5(3):236-242. doi: 10.1302/2633-1462.53.BJO-2023-0155.R1. Bone Jt Open. 2024. PMID: 38516934 Free PMC article.
75 results