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Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase.
Lederhofer J, Tsybovsky Y, Nguyen L, Raab JE, Creanga A, Stephens T, Gillespie RA, Syeda HZ, Fisher BE, Skertic M, Yap C, Schaub AJ, Rawi R, Kwong PD, Graham BS, McDermott AB, Andrews SF, King NP, Kanekiyo M. Lederhofer J, et al. Among authors: nguyen l. Immunity. 2024 Mar 12;57(3):574-586.e7. doi: 10.1016/j.immuni.2024.02.003. Epub 2024 Mar 1. Immunity. 2024. PMID: 38430907 Free article.
Structural Convergence and Water-Mediated Substrate Mimicry Enable Broad Neuraminidase Inhibition by Human Antibodies.
Lederhofer J, Borst AJ, Nguyen L, Gillespie RA, Williams CJ, Walker EL, Raab JE, Yap C, Ellis D, Creanga A, Tan HX, Do THT, Ravichandran M, McDermott AB, Sage VL, Andrews SF, Graham BS, Wheatley AK, Reed DS, King NP, Kanekiyo M. Lederhofer J, et al. Among authors: nguyen l. bioRxiv [Preprint]. 2024 Dec 3:2024.11.27.625426. doi: 10.1101/2024.11.27.625426. bioRxiv. 2024. PMID: 39677750 Free PMC article. Preprint.
AOH1996 targets mitochondrial dynamics and metabolism in leukemic stem cells via mitochondrial PCNA inhibition.
Kang H, Valerio M, Feng J, Gu L, Hoang DH, Blackmon A, Sharkas S, Pathak K, Jossart J, Li Z, Zhang H, Zhang B, Pirrotte P, Perry JJP, Hickey RJ, Malkas L, Marcucci G, Nguyen LXT. Kang H, et al. Among authors: nguyen lxt. Exp Hematol Oncol. 2024 Dec 28;13(1):123. doi: 10.1186/s40164-024-00586-4. Exp Hematol Oncol. 2024. PMID: 39732733 Free PMC article.
A conserved pilin from uncultured gut bacterial clade TANB77 enhances cancer immunotherapy.
Kim CY, Park DJ, Ahn BC, Baek S, Hong MH, Nguyen LT, Hwang SH, Kim N, Podlesny D, Orakov A, Schudoma C, Robbani SM, Shim HS, Yoon HI, Lee CY, Park SY, Yong D, Han M, Bork P, Kim BC, Ha SJ, Kim HR, Lee I. Kim CY, et al. Among authors: nguyen lt. Nat Commun. 2024 Dec 27;15(1):10726. doi: 10.1038/s41467-024-55388-3. Nat Commun. 2024. PMID: 39730328 Free PMC article.
5,339 results