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MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors.
Kim H, Lebeau B, Papadopoli D, Jovanovic P, Russo M, Avizonis D, Morita M, Afzali F, Ursini-Siegel J, Postovit LM, Witcher M, Topisirovic I. Kim H, et al. Among authors: jovanovic p. iScience. 2024 Feb 12;27(3):109188. doi: 10.1016/j.isci.2024.109188. eCollection 2024 Mar 15. iScience. 2024. PMID: 38433910 Free PMC article.
Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells.
Uchenunu O, Zhdanov AV, Hutton P, Jovanovic P, Wang Y, Andreev DE, Hulea L, Papadopoli DJ, Avizonis D, Baranov PV, Pollak MN, Papkovsky DB, Topisirovic I. Uchenunu O, et al. Among authors: jovanovic p. FEBS Open Bio. 2022 May;12(5):959-982. doi: 10.1002/2211-5463.13398. Epub 2022 Apr 1. FEBS Open Bio. 2022. PMID: 35302710 Free PMC article.
Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex.
Feng Y, Grotegut S, Jovanovic P, Gandin V, Olson SH, Murad R, Beall A, Colayco S, De-Jesus P, Chanda S, English BP, Singer RH, Jackson M, Topisirovic I, Ronai ZA. Feng Y, et al. Among authors: jovanovic p. Front Pharmacol. 2022 Dec 1;13:1029093. doi: 10.3389/fphar.2022.1029093. eCollection 2022. Front Pharmacol. 2022. PMID: 36532738 Free PMC article.
A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer.
Cencic R, Im YK, Naineni SK, Moustafa-Kamal M, Jovanovic P, Sabourin V, Annis MG, Robert F, Schmeing TM, Koromilas A, Paquet M, Teodoro JG, Huang S, Siegel PM, Topisirovic I, Ursini-Siegel J, Pelletier J. Cencic R, et al. Among authors: jovanovic p. Proc Natl Acad Sci U S A. 2024 Jan 23;121(4):e2318093121. doi: 10.1073/pnas.2318093121. Epub 2024 Jan 17. Proc Natl Acad Sci U S A. 2024. PMID: 38232291 Free PMC article.
SMYD5 methylation of rpL40 links ribosomal output to gastric cancer.
Park J, Wu J, Szkop KJ, Jeong J, Jovanovic P, Husmann D, Flores NM, Francis JW, Chen YC, Benitez AM, Zahn E, Song S, Ajani JA, Wang L, Singh K, Larsson O, Garcia BA, Topisirovic I, Gozani O, Mazur PK. Park J, et al. Among authors: jovanovic p. Nature. 2024 Aug;632(8025):656-663. doi: 10.1038/s41586-024-07718-0. Epub 2024 Jul 24. Nature. 2024. PMID: 39048817
Targeting eIF4G1-dependent translation in melanoma.
Feng Y, Radaeva M, Amiri M, Deshpande AJ, Olson S, Jovanovic P, Pass I, Deng Q, Lazar I, Murad R, Molinolo A, Kim H, Sergienko E, Villaneuva J, Topisirovic I, Jackson M, Sonenberg N, Cherkasov A, Ronai ZA. Feng Y, et al. Among authors: jovanovic p. bioRxiv [Preprint]. 2024 Nov 21:2024.11.20.624566. doi: 10.1101/2024.11.20.624566. bioRxiv. 2024. PMID: 39605602 Free PMC article. Preprint.
PABP prevents the untimely decay of select mRNA populations in human cells.
Kajjo S, Sharma S, Chen S, Brothers WR, Cott M, Hasaj B, Jovanovic P, Larsson O, Fabian MR. Kajjo S, et al. Among authors: jovanovic p. EMBO J. 2022 Mar 15;41(6):e108650. doi: 10.15252/embj.2021108650. Epub 2022 Feb 14. EMBO J. 2022. PMID: 35156721 Free PMC article.
Corrigendum: Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex.
Feng Y, Grotegut S, Jovanovic P, Gandin V, Olson SH, Murad R, Beall A, Colayco S, De-Jesus P, Chanda S, English BP, Singer RH, Jackson M, Topisirovic I, Ronai ZA. Feng Y, et al. Among authors: jovanovic p. Front Pharmacol. 2024 Dec 19;15:1528449. doi: 10.3389/fphar.2024.1528449. eCollection 2024. Front Pharmacol. 2024. PMID: 39749209 Free PMC article.
Association of plasma endocan levels with metabolic parameters and predictive value of endocan for the development of complications in patients with type 2 diabetes mellitus: An observational study.
Ljuca K, Aščerić M, Batić-Mujanović O, Loga-Zec S, Ljuca N, Bećirović E, Bejić S, Jovanović P, Bećirović M. Ljuca K, et al. Among authors: jovanovic p. Biomol Biomed. 2024 Dec 18. doi: 10.17305/bb.2024.11512. Online ahead of print. Biomol Biomed. 2024. PMID: 39720951 Free article.
139 results