Wang Y - Search Results

1

At the Speed of Light: The Systematic Implementation of Photoredox Cross-Coupling Reactions for Medicinal Chemistry Research.

Gesmundo NJ, Rago AJ, Young JM, Keess S, Wang Y. Gesmundo NJ, et al. Among authors: wang y. J Org Chem. 2024 Nov 15;89(22):16070-16092. doi: 10.1021/acs.joc.3c02351. Epub 2024 Mar 5. J Org Chem. 2024. PMID: 38442262 Review.

2

Synthesis of Fused Pyrimidinone and Quinolone Derivatives in an Automated High-Temperature and High-Pressure Flow Reactor.

Tsoung J, Bogdan AR, Kantor S, Wang Y, Charaschanya M, Djuric SW. Tsoung J, et al. Among authors: wang y. J Org Chem. 2017 Jan 20;82(2):1073-1084. doi: 10.1021/acs.joc.6b02520. Epub 2017 Jan 10. J Org Chem. 2017. PMID: 28001397

3

Expanding the Medicinal Chemist Toolbox: Comparing Seven C(sp²)-C(sp³) Cross-Coupling Methods by Library Synthesis.

Dombrowski AW, Gesmundo NJ, Aguirre AL, Sarris KA, Young JM, Bogdan AR, Martin MC, Gedeon S, Wang Y. Dombrowski AW, et al. Among authors: wang y. ACS Med Chem Lett. 2020 Mar 23;11(4):597-604. doi: 10.1021/acsmedchemlett.0c00093. eCollection 2020 Apr 9. ACS Med Chem Lett. 2020. PMID: 32292569 Free PMC article.

4

The Chosen Few: Parallel Library Reaction Methodologies for Drug Discovery.

Dombrowski AW, Aguirre AL, Shrestha A, Sarris KA, Wang Y. Dombrowski AW, et al. Among authors: wang y. J Org Chem. 2022 Feb 18;87(4):1880-1897. doi: 10.1021/acs.joc.1c01427. Epub 2021 Nov 15. J Org Chem. 2022. PMID: 34780177

5

What is in Our Kit? An Analysis of Building Blocks Used in Medicinal Chemistry Parallel Libraries.

Wang Y, Haight I, Gupta R, Vasudevan A. Wang Y, et al. J Med Chem. 2021 Dec 9;64(23):17115-17122. doi: 10.1021/acs.jmedchem.1c01139. Epub 2021 Nov 22. J Med Chem. 2021. PMID: 34807604

6

Di(2-picolyl)amines as Modular and Robust Ligands for Nickel-Catalyzed C(sp²)-C(sp³) Cross-Electrophile Coupling.

Rago AJ, Vasilopoulos A, Dombrowski AW, Wang Y. Rago AJ, et al. Among authors: wang y. Org Lett. 2022 Nov 25;24(46):8487-8492. doi: 10.1021/acs.orglett.2c03346. Epub 2022 Nov 15. Org Lett. 2022. PMID: 36377969

7

ChemBeads-Enabled Photoredox High-Throughput Experimentation Platform to Improve C(sp²)-C(sp³) Decarboxylative Couplings.

Gesmundo NJ, Tu NP, Sarris KA, Wang Y. Gesmundo NJ, et al. Among authors: wang y. ACS Med Chem Lett. 2023 Mar 16;14(4):521-529. doi: 10.1021/acsmedchemlett.2c00538. eCollection 2023 Apr 13. ACS Med Chem Lett. 2023. PMID: 37077401 Free PMC article.

8

Incorporating Synthetic Accessibility in Drug Design: Predicting Reaction Yields of Suzuki Cross-Couplings by Leveraging AbbVie's 15-Year Parallel Library Data Set.

Raghavan P, Rago AJ, Verma P, Hassan MM, Goshu GM, Dombrowski AW, Pandey A, Coley CW, Wang Y. Raghavan P, et al. Among authors: wang y. J Am Chem Soc. 2024 Jun 5;146(22):15070-15084. doi: 10.1021/jacs.4c00098. Epub 2024 May 20. J Am Chem Soc. 2024. PMID: 38768950 Free PMC article.

9

High-Temperature Boc Deprotection in Flow and Its Application in Multistep Reaction Sequences.

Bogdan AR, Charaschanya M, Dombrowski AW, Wang Y, Djuric SW. Bogdan AR, et al. Among authors: wang y. Org Lett. 2016 Apr 15;18(8):1732-5. doi: 10.1021/acs.orglett.6b00378. Epub 2016 Apr 5. Org Lett. 2016. PMID: 27046640

10

Automated library synthesis of cyclopropyl boronic esters employing diazomethane in a tube-in-tube flow reactor.

Koolman HF, Kantor S, Bogdan AR, Wang Y, Pan JY, Djuric SW. Koolman HF, et al. Among authors: wang y. Org Biomol Chem. 2016 Jul 6;14(27):6591-5. doi: 10.1039/c6ob00715e. Org Biomol Chem. 2016. PMID: 27314279

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