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Page 1
Stroke Causes DNA Methylation at Ncx1 Heart Promoter in the Brain Via DNMT1/MeCP2/REST Epigenetic Complex.
Guida N, Serani A, Sanguigno L, Mascolo L, Cuomo O, Fioriniello S, Marano D, Ragione FD, Anzilotti S, Brancaccio P, Molinaro P, Pignataro G, Annunziato L, Formisano L. Guida N, et al. Among authors: serani a. J Am Heart Assoc. 2024 Mar 19;13(6):e030460. doi: 10.1161/JAHA.123.030460. Epub 2024 Mar 8. J Am Heart Assoc. 2024. PMID: 38456444 Free PMC article.
The neurotoxicant PCB-95 by increasing the neuronal transcriptional repressor REST down-regulates caspase-8 and increases Ripk1, Ripk3 and MLKL expression determining necroptotic neuronal death.
Guida N, Laudati G, Serani A, Mascolo L, Molinaro P, Montuori P, Di Renzo G, Canzoniero LMT, Formisano L. Guida N, et al. Among authors: serani a. Biochem Pharmacol. 2017 Oct 15;142:229-241. doi: 10.1016/j.bcp.2017.06.135. Epub 2017 Jul 1. Biochem Pharmacol. 2017. PMID: 28676433
HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage.
Formisano L, Laudati G, Guida N, Mascolo L, Serani A, Cuomo O, Cantile M, Boscia F, Molinaro P, Anzilotti S, Pizzorusso V, Di Renzo G, Pignataro G, Annunziato L. Formisano L, et al. Among authors: serani a. J Cereb Blood Flow Metab. 2020 Oct;40(10):2081-2097. doi: 10.1177/0271678X19884742. Epub 2019 Nov 7. J Cereb Blood Flow Metab. 2020. PMID: 31696766 Free PMC article.
Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats.
Cuomo O, Cepparulo P, Anzilotti S, Serani A, Sirabella R, Brancaccio P, Guida N, Valsecchi V, Vinciguerra A, Molinaro P, Formisano L, Annunziato L, Pignataro G. Cuomo O, et al. Among authors: serani a. Mol Ther Nucleic Acids. 2019 Dec 6;18:1063-1071. doi: 10.1016/j.omtn.2019.10.022. Epub 2019 Oct 28. Mol Ther Nucleic Acids. 2019. PMID: 31791013 Free PMC article.
Transcriptional and epigenetic regulation of ncx1 and ncx3 in the brain.
Formisano L, Guida N, Mascolo L, Serani A, Laudati G, Pizzorusso V, Annunziato L. Formisano L, et al. Among authors: serani a. Cell Calcium. 2020 May;87:102194. doi: 10.1016/j.ceca.2020.102194. Epub 2020 Mar 7. Cell Calcium. 2020. PMID: 32172011 Review.
GATA3 (GATA-Binding Protein 3)/KMT2A (Lysine-Methyltransferase-2A) Complex by Increasing H3K4-3me (Trimethylated Lysine-4 of Histone-3) Upregulates NCX3 (Na+-Ca2+ Exchanger 3) Transcription and Contributes to Ischemic Preconditioning Neuroprotection.
Guida N, Mascolo L, Serani A, Cuomo O, Anzilotti S, Brancaccio P, Pignataro G, Molinaro P, Annunziato L, Formisano L. Guida N, et al. Among authors: serani a. Stroke. 2021 Nov;52(11):3680-3691. doi: 10.1161/STROKEAHA.121.034637. Epub 2021 Oct 25. Stroke. 2021. PMID: 34694864
The Transcriptional Complex Sp1/KMT2A by Up-Regulating Restrictive Element 1 Silencing Transcription Factor Accelerates Methylmercury-Induced Cell Death in Motor Neuron-Like NSC34 Cells Overexpressing SOD1-G93A.
Guida N, Sanguigno L, Mascolo L, Calabrese L, Serani A, Molinaro P, Lau CG, Annunziato L, Formisano L. Guida N, et al. Among authors: serani a. Front Neurosci. 2021 Nov 26;15:771580. doi: 10.3389/fnins.2021.771580. eCollection 2021. Front Neurosci. 2021. PMID: 34899171 Free PMC article.
28 results