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Page 1
DUSP6 mediates resistance to JAK2 inhibition and drives leukemic progression.
Kong T, Laranjeira ABA, Yang K, Fisher DAC, Yu L, Poittevin De La Frégonnière L, Wang AZ, Ruzinova MB, Fowles JS, Fulbright MC, Cox MJ, Celik H, Challen GA, Huang S, Oh ST. Kong T, et al. Among authors: fulbright mc. Nat Cancer. 2023 Jan;4(1):108-127. doi: 10.1038/s43018-022-00486-8. Epub 2022 Dec 29. Nat Cancer. 2023. PMID: 36581736 Free PMC article.
Multiomic profiling reveals metabolic alterations mediating aberrant platelet activity and inflammation in myeloproliferative neoplasms.
He F, Laranjeira AB, Kong T, Lin S, Ashworth KJ, Liu A, Lasky NM, Fisher DA, Cox MJ, Fulbright MC, Antunes-Heck L, Yu L, Brakhane M, Gao B, Sykes SM, D'Alessandro A, Di Paola J, Oh ST. He F, et al. Among authors: fulbright mc. J Clin Invest. 2024 Feb 1;134(3):e172256. doi: 10.1172/JCI172256. J Clin Invest. 2024. PMID: 38060311 Free PMC article.
RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemia.
Kong T, Laranjeira ABA, Letson CT, Yu L, Lin S, Fowles JS, Fisher DAC, Ng S, Yang W, He F, Youn M, Mark K, Jose AS, Liu J, Kim AB, Cox MJ, Fulbright MC, Jayanthan A, Los G, Rentschler SL, Ding L, Sakamoto KM, Dunn SE, Challen GA, Oh ST. Kong T, et al. Among authors: fulbright mc. Nat Commun. 2025 Jan 16;16(1):492. doi: 10.1038/s41467-024-55643-7. Nat Commun. 2025. PMID: 39820365 Free PMC article.
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