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Page 1
A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions.
Eraña H, Sampedro-Torres-Quevedo C, Charco JM, Díaz-Domínguez CM, Peccati F, San-Juan-Ansoleaga M, Vidal E, Gonçalves-Anjo N, Pérez-Castro MA, González-Miranda E, Piñeiro P, Fernández-Veiga L, Galarza-Ahumada J, Fernández-Muñoz E, Perez de Nanclares G, Telling G, Geijo M, Jiménez-Osés G, Castilla J. Eraña H, et al. Among authors: charco jm. Nat Commun. 2024 Mar 8;15(1):2112. doi: 10.1038/s41467-024-46360-2. Nat Commun. 2024. PMID: 38459071 Free PMC article.
Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation.
Eraña H, Díaz-Domínguez CM, Charco JM, Vidal E, González-Miranda E, Pérez-Castro MA, Piñeiro P, López-Moreno R, Sampedro-Torres-Quevedo C, Fernández-Veiga L, Tasis-Galarza J, Lorenzo NL, Santini-Santiago A, Lázaro M, García-Martínez S, Gonçalves-Anjo N, San-Juan-Ansoleaga M, Galarza-Ahumada J, Fernández-Muñoz E, Giler S, Valle M, Telling GC, Geijó M, Requena JR, Castilla J. Eraña H, et al. Among authors: charco jm. Acta Neuropathol Commun. 2023 Sep 7;11(1):145. doi: 10.1186/s40478-023-01640-8. Acta Neuropathol Commun. 2023. PMID: 37679832 Free PMC article.
Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model.
Vidal E, Sánchez-Martín MA, Eraña H, Lázaro SP, Pérez-Castro MA, Otero A, Charco JM, Marín B, López-Moreno R, Díaz-Domínguez CM, Geijo M, Ordóñez M, Cantero G, di Bari M, Lorenzo NL, Pirisinu L, d'Agostino C, Torres JM, Béringue V, Telling G, Badiola JJ, Pumarola M, Bolea R, Nonno R, Requena JR, Castilla J. Vidal E, et al. Among authors: charco jm. Acta Neuropathol Commun. 2022 Dec 13;10(1):179. doi: 10.1186/s40478-022-01477-7. Acta Neuropathol Commun. 2022. PMID: 36514160 Free PMC article.
Analysis of a large case series of fatal familial insomnia to determine tests with the highest diagnostic value.
Kortazar-Zubizarreta I, Eraña H, Pereda A, Charco JM, Manero-Azua A, Ruiz-Onandi R, Aguirre U, Gonzalez-Chinchon G; Basque Prionopathies Study Group; Perez de Nanclares G, Castilla J. Kortazar-Zubizarreta I, et al. Among authors: charco jm. J Neuropathol Exp Neurol. 2023 Jan 20;82(2):169-179. doi: 10.1093/jnen/nlac113. J Neuropathol Exp Neurol. 2023. PMID: 36458954
Description of the first Spanish case of Gerstmann-Sträussler-Scheinker disease with A117V variant: clinical, histopathological and biochemical characterization.
Eraña H, San Millán B, Díaz-Domínguez CM, Charco JM, Rodríguez R, Viéitez I, Pereda A, Yañez R, Geijo M, Navarro C, Perez de Nanclares G, Teijeira S, Castilla J. Eraña H, et al. Among authors: charco jm. J Neurol. 2022 Aug;269(8):4253-4263. doi: 10.1007/s00415-022-11051-9. Epub 2022 Mar 16. J Neurol. 2022. PMID: 35294616 Free PMC article.
Homozygous R136S mutation in PRNP gene causes inherited early onset prion disease.
Ximelis T, Marín-Moreno A, Espinosa JC, Eraña H, Charco JM, Hernández I, Riveira C, Alcolea D, González-Roca E, Aldecoa I, Molina-Porcel L, Parchi P, Rossi M, Castilla J, Ruiz-García R, Gelpi E, Torres JM, Sánchez-Valle R. Ximelis T, et al. Among authors: charco jm. Alzheimers Res Ther. 2021 Oct 18;13(1):176. doi: 10.1186/s13195-021-00912-6. Alzheimers Res Ther. 2021. PMID: 34663460 Free PMC article.
18 results