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Impact of SARS-CoV-2 spike stability and RBD exposure on antigenicity and immunogenicity.
Rutten L, Swart M, Koornneef A, Bouchier P, Blokland S, Sadi A, Juraszek J, Vijayan A, Schmit-Tillemans S, Verspuij J, Choi Y, Daal CE, Perkasa A, Torres Morales S, Myeni SK, Kikkert M, Tolboom J, van Manen D, Kuipers H, Schuitemaker H, Zahn R, Langedijk JPM. Rutten L, et al. Among authors: langedijk jpm. Sci Rep. 2024 Mar 8;14(1):5735. doi: 10.1038/s41598-024-56293-x. Sci Rep. 2024. PMID: 38459086 Free PMC article.
CoPoP liposomes displaying stabilized clade C HIV-1 Env elicit tier 2 multiclade neutralization in rabbits.
Koornneef A, Vanshylla K, Hardenberg G, Rutten L, Strokappe NM, Tolboom J, Vreugdenhil J, Boer KF, Perkasa A, Blokland S, Burger JA, Huang WC, Lovell JF, van Manen D, Sanders RW, Zahn RC, Schuitemaker H, Langedijk JPM, Wegmann F. Koornneef A, et al. Among authors: langedijk jpm. Nat Commun. 2024 Apr 11;15(1):3128. doi: 10.1038/s41467-024-47492-1. Nat Commun. 2024. PMID: 38605096 Free PMC article.
A foldon-free prefusion F trimer vaccine for respiratory syncytial virus to reduce off-target immune responses.
Bakkers MJG, Cox F, Koornneef A, Yu X, van Overveld D, Le L, van den Hoogen W, Vaneman J, Thoma A, Voorzaat R, Tettero L, Juraszek J, van der Fits L, Zahn R, Langedijk JPM. Bakkers MJG, et al. Among authors: langedijk jpm. Nat Microbiol. 2024 Dec;9(12):3254-3267. doi: 10.1038/s41564-024-01860-1. Epub 2024 Nov 20. Nat Microbiol. 2024. PMID: 39567664 Free PMC article.
Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer.
Bakkers MJG, Ritschel T, Tiemessen M, Dijkman J, Zuffianò AA, Yu X, van Overveld D, Le L, Voorzaat R, van Haaren MM, de Man M, Tamara S, van der Fits L, Zahn R, Juraszek J, Langedijk JPM. Bakkers MJG, et al. Among authors: langedijk jpm. Nat Commun. 2024 Jul 25;15(1):6270. doi: 10.1038/s41467-024-50659-5. Nat Commun. 2024. PMID: 39054318 Free PMC article.
Absolute quantitation of binding antibodies from clinical samples.
Tang C, Verwilligen A, Sadoff J, Brandenburg B, Sneekes-Vriese E, van den Kerkhof T, Dillen L, Rutten L, Juraszek J, Callewaert K, Janssen S, Huizingh J, Euler Z, Schilperoord T, Verhemeldonck M, Langedijk JPM, Hendriks J, Stieh DJ. Tang C, et al. Among authors: langedijk jpm. NPJ Vaccines. 2024 Jan 6;9(1):8. doi: 10.1038/s41541-023-00793-w. NPJ Vaccines. 2024. PMID: 38184641 Free PMC article.
Enhancing breadth and durability of humoral immune responses in non-human primates with an adjuvanted group 1 influenza hemagglutinin stem antigen.
Swart M, Kuipers H, Milder F, Jongeneelen M, Ritschel T, Tolboom J, Muchene L, van der Lubbe J, Izquierdo Gil A, Veldman D, Huizingh J, Verspuij J, Schmit-Tillemans S, Blokland S, de Man M, Roozendaal R, Fox CB, Schuitemaker H, Capelle M, Langedijk JPM, Zahn R, Brandenburg B. Swart M, et al. Among authors: langedijk jpm. NPJ Vaccines. 2023 Nov 11;8(1):176. doi: 10.1038/s41541-023-00772-1. NPJ Vaccines. 2023. PMID: 37952003 Free PMC article.
60 results