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One-step rapid tracking and isolation of senescent cells in cellular systems, tissues, or animal models via GLF16.
Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Giannetti K, Pippa N, Lougiakis N, Kambas K, Lagopati N, Polyzou A, Georgiou M, Chountoulesi M, Pispas S, Foutadakis S, Kyrodimos E, Pouli N, Marakos P, Kotsinas A, Verginis P, Valakos D, Vatsellas G, Petty R, Thanos D, Demaria M, Evangelou K, Di Micco R, Gorgoulis VG. Magkouta S, et al. Among authors: kambas k. STAR Protoc. 2024 Mar 15;5(1):102929. doi: 10.1016/j.xpro.2024.102929. Epub 2024 Mar 8. STAR Protoc. 2024. PMID: 38460134 Free PMC article.
A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells.
Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Pippa N, Lougiakis N, Kambas K, Lagopati N, Polyzou A, Georgiou M, Chountoulesi M, Pispas S, Foutadakis S, Pouli N, Marakos P, Kotsinas A, Verginis P, Valakos D, Mizi A, Papantonis A, Vatsellas G, Galanos P, Bartek J, Petty R, Serrano M, Thanos D, Roussos C, Demaria M, Evangelou K, Gorgoulis VG. Magkouta S, et al. Among authors: kambas k. Mol Cell. 2023 Oct 5;83(19):3558-3573.e7. doi: 10.1016/j.molcel.2023.09.006. Mol Cell. 2023. PMID: 37802028 Free article.
Senescent cells in giant cell arteritis display an inflammatory phenotype participating in tissue injury via IL-6-dependent pathways.
Veroutis D, Argyropoulou OD, Goules AV, Kambas K, Palamidas DA, Evangelou K, Havaki S, Polyzou A, Valakos D, Xingi E, Karatza E, Boki KA, Cavazza A, Kittas C, Thanos D, Ricordi C, Marvisi C, Muratore F, Galli E, Croci S, Salvarani C, Gorgoulis VG, Tzioufas AG. Veroutis D, et al. Among authors: kambas k. Ann Rheum Dis. 2024 Feb 15;83(3):342-350. doi: 10.1136/ard-2023-224467. Ann Rheum Dis. 2024. PMID: 38050005
Generation of a selective senolytic platform using a micelle-encapsulated Sudan Black B conjugated analog.
Magkouta S, Veroutis D, Papaspyropoulos A, Georgiou M, Lougiakis N, Pippa N, Havaki S, Palaiologou A, Thanos DF, Kambas K, Lagopati N, Boukos N, Pouli N, Marakos P, Kotsinas A, Thanos D, Evangelou K, Sampaziotis F, Tamvakopoulos C, Pispas S, Petty R, Kotopoulos N, Gorgoulis VG. Magkouta S, et al. Among authors: kambas k. Nat Aging. 2024 Dec 27. doi: 10.1038/s43587-024-00747-4. Online ahead of print. Nat Aging. 2024. PMID: 39730824
L-Dopa decarboxylase modulates autophagy in hepatocytes and is implicated in dengue virus-caused inhibition of autophagy completion.
Tsopela V, Korakidis E, Lagou D, Kalliampakou KI, Milona RS, Kyriakopoulou E, Mpekoulis G, Gemenetzi I, Stylianaki EA, Sideris CD, Sioli A, Kefallinos D, Sideris DC, Aidinis V, Eliopoulos AG, Kambas K, Vassilacopoulou D, Vassilaki N. Tsopela V, et al. Among authors: kambas k. Biochim Biophys Acta Mol Cell Res. 2024 Jan;1871(1):119602. doi: 10.1016/j.bbamcr.2023.119602. Epub 2023 Sep 29. Biochim Biophys Acta Mol Cell Res. 2024. PMID: 37778471 Free article.
18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Large-Vessel Vasculitis During Active and Inactive Disease Stages Is Associated with the Metabolic Profile, but Not the Macrophage-Related Cytokines: A Proof-of-Concept Study.
Palamidas DA, Kalykakis G, Benaki D, Chatzis L, Argyropoulou OD, Palla P, Kollia A, Kafouris P, Metaxas M, Goules AV, Mikros E, Kambas K, Anagnostopoulos CD, Tzioufas AG. Palamidas DA, et al. Among authors: kambas k. Cells. 2024 Nov 8;13(22):1851. doi: 10.3390/cells13221851. Cells. 2024. PMID: 39594602 Free PMC article.
Down-regulation of KLF2 in lung fibroblasts is linked with COVID-19 immunofibrosis and restored by combined inhibition of NETs, JAK-1/2 and IL-6 signaling.
Chrysanthopoulou A, Antoniadou C, Natsi AM, Gavriilidis E, Papadopoulos V, Xingi E, Didaskalou S, Mikroulis D, Tsironidou V, Kambas K, Koffa M, Skendros P, Ritis K. Chrysanthopoulou A, et al. Among authors: kambas k. Clin Immunol. 2023 Feb;247:109240. doi: 10.1016/j.clim.2023.109240. Epub 2023 Jan 21. Clin Immunol. 2023. PMID: 36693535 Free PMC article.
Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice.
Papazian I, Tsoukala E, Boutou A, Karamita M, Kambas K, Iliopoulou L, Fischer R, Kontermann RE, Denis MC, Kollias G, Lassmann H, Probert L. Papazian I, et al. Among authors: kambas k. J Neuroinflammation. 2021 Sep 26;18(1):222. doi: 10.1186/s12974-021-02200-4. J Neuroinflammation. 2021. PMID: 34565380 Free PMC article.
48 results