Laman H - Search Results

1

Study of an FBXO7 patient mutation reveals Fbxo7 and PI31 co-regulate proteasomes and mitochondria.

Al Rawi S, Simpson L, Agnarsdóttir G, McDonald NQ, Chernuha V, Elpeleg O, Zeviani M, Barker RA, Spiegel R, Laman H. Al Rawi S, et al. Among authors: laman h. FEBS J. 2024 Jun;291(12):2565-2589. doi: 10.1111/febs.17114. Epub 2024 Mar 11. FEBS J. 2024. PMID: 38466799

2

Loss of FBXO7 results in a Parkinson's-like dopaminergic degeneration via an RPL23-MDM2-TP53 pathway.

Stott SR, Randle SJ, Al Rawi S, Rowicka PA, Harris R, Mason B, Xia J, Dalley JW, Barker RA, Laman H. Stott SR, et al. Among authors: laman h. J Pathol. 2019 Oct;249(2):241-254. doi: 10.1002/path.5312. Epub 2019 Aug 6. J Pathol. 2019. PMID: 31144295 Free PMC article.

3

Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor.

Kirk R, Laman H, Knowles PP, Murray-Rust J, Lomonosov M, Meziane el K, McDonald NQ. Kirk R, et al. Among authors: laman h. J Biol Chem. 2008 Aug 8;283(32):22325-35. doi: 10.1074/jbc.M709900200. Epub 2008 May 20. J Biol Chem. 2008. PMID: 18495667 Free article.

4

A Conserved Requirement for Fbxo7 During Male Germ Cell Cytoplasmic Remodeling.

Rathje CC, Randle SJ, Al Rawi S, Skinner BM, Nelson DE, Majumdar A, Johnson EEP, Bacon J, Vlazaki M, Affara NA, Ellis PJ, Laman H. Rathje CC, et al. Among authors: laman h. Front Physiol. 2019 Oct 10;10:1278. doi: 10.3389/fphys.2019.01278. eCollection 2019. Front Physiol. 2019. PMID: 31649556 Free PMC article.

5

Crystal structure of a gamma-herpesvirus cyclin-cdk complex.

Card GL, Knowles P, Laman H, Jones N, McDonald NQ. Card GL, et al. Among authors: laman h. EMBO J. 2000 Jun 15;19(12):2877-88. doi: 10.1093/emboj/19.12.2877. EMBO J. 2000. PMID: 10856233 Free PMC article.

6

Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6.

Laman H, Funes JM, Ye H, Henderson S, Galinanes-Garcia L, Hara E, Knowles P, McDonald N, Boshoff C. Laman H, et al. EMBO J. 2005 Sep 7;24(17):3104-16. doi: 10.1038/sj.emboj.7600775. Epub 2005 Aug 11. EMBO J. 2005. PMID: 16096642 Free PMC article.

7

The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy.

Burchell VS, Nelson DE, Sanchez-Martinez A, Delgado-Camprubi M, Ivatt RM, Pogson JH, Randle SJ, Wray S, Lewis PA, Houlden H, Abramov AY, Hardy J, Wood NW, Whitworth AJ, Laman H, Plun-Favreau H. Burchell VS, et al. Among authors: laman h. Nat Neurosci. 2013 Sep;16(9):1257-65. doi: 10.1038/nn.3489. Epub 2013 Aug 11. Nat Neurosci. 2013. PMID: 23933751 Free PMC article.

8

Defective erythropoiesis in a mouse model of reduced Fbxo7 expression due to decreased p27 expression.

Randle SJ, Nelson DE, Patel SP, Laman H. Randle SJ, et al. Among authors: laman h. J Pathol. 2015 Oct;237(2):263-72. doi: 10.1002/path.4571. Epub 2015 Jul 8. J Pathol. 2015. PMID: 26095538 Free PMC article.

9

Knockdown of Fbxo7 reveals its regulatory role in proliferation and differentiation of haematopoietic precursor cells.

Meziane el K, Randle SJ, Nelson DE, Lomonosov M, Laman H. Meziane el K, et al. Among authors: laman h. J Cell Sci. 2011 Jul 1;124(Pt 13):2175-86. doi: 10.1242/jcs.080465. Epub 2011 Jun 7. J Cell Sci. 2011. PMID: 21652635

10

Fbxo7 gets proactive with cyclin D/cdk6.

Laman H. Laman H. Cell Cycle. 2006 Feb;5(3):279-82. doi: 10.4161/cc.5.3.2403. Epub 2006 Feb 8. Cell Cycle. 2006. PMID: 16410730

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