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STAT3 protects hematopoietic stem cells by preventing activation of a deleterious autocrine type-I interferon response.
Patel B, Zhou Y, Babcock RL, Ma F, Zal MA, Kumar D, Medik YB, Kahn LM, Pineda JE, Park EM, Schneider SM, Tang X, Raso MG, Jeter CR, Zal T, Clise-Dwyer K, Keyomarsi K, Giancotti FG, Colla S, Watowich SS. Patel B, et al. Among authors: giancotti fg. Leukemia. 2024 May;38(5):1143-1155. doi: 10.1038/s41375-024-02218-6. Epub 2024 Mar 11. Leukemia. 2024. PMID: 38467768 Free PMC article.
Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis.
Han H, Wang Y, Curto J, Gurrapu S, Laudato S, Rumandla A, Chakraborty G, Wang X, Chen H, Jiang Y, Kumar D, Caggiano EG, Capogiri M, Zhang B, Ji Y, Maity SN, Hu M, Bai S, Aparicio AM, Efstathiou E, Logothetis CJ, Navin N, Navone NM, Chen Y, Giancotti FG. Han H, et al. Among authors: giancotti fg. Cell Rep. 2022 Apr 5;39(1):110595. doi: 10.1016/j.celrep.2022.110595. Cell Rep. 2022. PMID: 35385726 Free PMC article.
Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma.
Jain N, Hartert K, Tadros S, Fiskus W, Havranek O, Ma MCJ, Bouska A, Heavican T, Kumar D, Deng Q, Moore D, Pak C, Liu CL, Gentles AJ, Hartmann E, Kridel R, Smedby KE, Juliusson G, Rosenquist R, Gascoyne RD, Rosenwald A, Giancotti F, Neelapu SS, Westin J, Vose JM, Lunning MA, Greiner T, Rodig S, Iqbal J, Alizadeh AA, Davis RE, Bhalla K, Green MR. Jain N, et al. Sci Transl Med. 2019 Jun 19;11(497):eaav5599. doi: 10.1126/scitranslmed.aav5599. Sci Transl Med. 2019. PMID: 31217338 Free PMC article.
β4 Integrin signaling induces expansion of prostate tumor progenitors.
Yoshioka T, Otero J, Chen Y, Kim YM, Koutcher JA, Satagopan J, Reuter V, Carver B, de Stanchina E, Enomoto K, Greenberg NM, Scardino PT, Scher HI, Sawyers CL, Giancotti FG. Yoshioka T, et al. Among authors: giancotti fg. J Clin Invest. 2013 Feb;123(2):682-99. doi: 10.1172/JCI60720. Epub 2013 Jan 25. J Clin Invest. 2013. PMID: 23348745 Free PMC article.
Prostate epithelial genes define therapy-relevant prostate cancer molecular subtype.
Han H, Lee HH, Choi K, Moon YJ, Heo JE, Ham WS, Jang WS, Rha KH, Cho NH, Giancotti FG, Choi YD. Han H, et al. Among authors: giancotti fg. Prostate Cancer Prostatic Dis. 2021 Dec;24(4):1080-1092. doi: 10.1038/s41391-021-00364-x. Epub 2021 Apr 26. Prostate Cancer Prostatic Dis. 2021. PMID: 33903734 Free PMC article.
115 results