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Page 1
STAT3 protects hematopoietic stem cells by preventing activation of a deleterious autocrine type-I interferon response.
Patel B, Zhou Y, Babcock RL, Ma F, Zal MA, Kumar D, Medik YB, Kahn LM, Pineda JE, Park EM, Schneider SM, Tang X, Raso MG, Jeter CR, Zal T, Clise-Dwyer K, Keyomarsi K, Giancotti FG, Colla S, Watowich SS. Patel B, et al. Among authors: pineda je. Leukemia. 2024 May;38(5):1143-1155. doi: 10.1038/s41375-024-02218-6. Epub 2024 Mar 11. Leukemia. 2024. PMID: 38467768 Free PMC article.
Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration.
Zhou Y, Medik YB, Patel B, Zamler DB, Chen S, Chapman T, Schneider S, Park EM, Babcock RL, Chrisikos TT, Kahn LM, Dyevoich AM, Pineda JE, Wong MC, Mishra AK, Cass SH, Cogdill AP, Johnson DH, Johnson SB, Wani K, Ledesma DA, Hudgens CW, Wang J, Wadud Khan MA, Peterson CB, Joon AY, Peng W, Li HS, Arora R, Tang X, Raso MG, Zhang X, Foo WC, Tetzlaff MT, Diehl GE, Clise-Dwyer K, Whitley EM, Gubin MM, Allison JP, Hwu P, Ajami NJ, Diab A, Wargo JA, Watowich SS. Zhou Y, et al. Among authors: pineda je. J Exp Med. 2023 Feb 6;220(2):e20221333. doi: 10.1084/jem.20221333. Epub 2022 Nov 11. J Exp Med. 2023. PMID: 36367776 Free PMC article.
BHLHE40 Regulates the T-Cell Effector Function Required for Tumor Microenvironment Remodeling and Immune Checkpoint Therapy Efficacy.
Salmon AJ, Shavkunov AS, Miao Q, Jarjour NN, Keshari S, Esaulova E, Williams CD, Ward JP, Highsmith AM, Pineda JE, Taneja R, Chen K, Edelson BT, Gubin MM. Salmon AJ, et al. Among authors: pineda je. Cancer Immunol Res. 2022 May 3;10(5):597-611. doi: 10.1158/2326-6066.CIR-21-0129. Cancer Immunol Res. 2022. PMID: 35181783 Free PMC article.
Comparing neoantigen cancer vaccines and immune checkpoint therapy unveils an effective vaccine and anti-TREM2 macrophage-targeting dual therapy.
Keshari S, Shavkunov AS, Miao Q, Saha A, Minowa T, Molgora M, Williams CD, Chaib M, Highsmith AM, Pineda JE, Alekseev S, Alspach E, Hu KH, Colonna M, Pauken KE, Chen K, Gubin MM. Keshari S, et al. Among authors: pineda je. Cell Rep. 2024 Nov 26;43(11):114875. doi: 10.1016/j.celrep.2024.114875. Epub 2024 Oct 23. Cell Rep. 2024. PMID: 39446585 Free article.
Neoantigen Cancer Vaccines and Different Immune Checkpoint Therapies Each Utilize Both Converging and Distinct Mechanisms that in Combination Enable Synergistic Therapeutic Efficacy.
Keshari S, Shavkunov AS, Miao Q, Saha A, Williams CD, Highsmith AM, Pineda JE, Alspach E, Hu KH, Pauken KE, Chen K, Gubin MM. Keshari S, et al. Among authors: pineda je. bioRxiv [Preprint]. 2024 Jan 26:2023.12.20.570816. doi: 10.1101/2023.12.20.570816. bioRxiv. 2024. Update in: Cell Rep. 2024 Nov 26;43(11):114875. doi: 10.1016/j.celrep.2024.114875 PMID: 38187708 Free PMC article. Updated. Preprint.
Four annular structures in a protostellar disk less than 500,000 years old.
Segura-Cox DM, Schmiedeke A, Pineda JE, Stephens IW, Fernández-López M, Looney LW, Caselli P, Li ZY, Mundy LG, Kwon W, Harris RJ. Segura-Cox DM, et al. Among authors: pineda je. Nature. 2020 Oct;586(7828):228-231. doi: 10.1038/s41586-020-2779-6. Epub 2020 Oct 7. Nature. 2020. PMID: 33028998
11 results