Xu SY - Search Results

1

Computer-aided design to enhance the stability of aldo-keto reductase KdAKR.

Dai C, Tian JX, Chen YF, Ni YH, Cui L, Cao HX, Song LL, Xu SY, Wang YJ, Zheng YG. Dai C, et al. Among authors: xu sy. Biotechnol J. 2024 Mar;19(3):e2300637. doi: 10.1002/biot.202300637. Biotechnol J. 2024. PMID: 38472092

2

Comparative proteome analysis of Actinoplanes utahensis grown on various saccharides based on 2D-DIGE and MALDI-TOF/TOF-MS.

Weng CY, Wang CE, Xie WB, Xu SY, Wang YJ, Zheng YG. Weng CY, et al. Among authors: xu sy. J Proteomics. 2021 May 15;239:104193. doi: 10.1016/j.jprot.2021.104193. Epub 2021 Mar 20. J Proteomics. 2021. PMID: 33757877

3

Fluorescence-based screening for engineered aldo-keto reductase KmAKR with improved catalytic performance and extended substrate scope.

Qiu S, Xu SY, Li SF, Meng KM, Cheng F, Wang YJ, Zheng YG. Qiu S, et al. Among authors: xu sy. Biotechnol J. 2021 Sep;16(9):e2100130. doi: 10.1002/biot.202100130. Epub 2021 Jun 26. Biotechnol J. 2021. PMID: 34125995

4

Semirational engineering of an aldo-keto reductase KmAKR for overcoming trade-offs between catalytic activity and thermostability.

Li SF, Xie JY, Qiu S, Xu SY, Cheng F, Wang YJ, Zheng YG. Li SF, et al. Among authors: xu sy. Biotechnol Bioeng. 2021 Nov;118(11):4441-4452. doi: 10.1002/bit.27913. Epub 2021 Aug 16. Biotechnol Bioeng. 2021. PMID: 34374988

5

Directed evolution of a carbonyl reductase LsCR for the enantioselective synthesis of (1S)-2-chloro-1-(3,4-difluorophenyl) ethanol.

Liu HT, Weng CY, Xu SY, Li SF, Wang YJ, Zheng YG. Liu HT, et al. Among authors: xu sy. Bioorg Chem. 2022 Oct;127:105991. doi: 10.1016/j.bioorg.2022.105991. Epub 2022 Jun 27. Bioorg Chem. 2022. PMID: 35816872

6

Development of a new chemo-enzymatic catalytic route for synthesis of (S)- 2-chlorophenylglycine.

Cheng F, Xie WB, Gao XF, Chu RL, Xu SY, Wang YJ, Zheng YG. Cheng F, et al. Among authors: xu sy. J Biotechnol. 2022 Nov 10;358:17-24. doi: 10.1016/j.jbiotec.2022.08.013. Epub 2022 Aug 18. J Biotechnol. 2022. PMID: 35987310

7

Recent advances in structure-based enzyme engineering for functional reconstruction.

Xu SY, Zhou L, Xu Y, Hong HY, Dai C, Wang YJ, Zheng YG. Xu SY, et al. Among authors: xu y. Biotechnol Bioeng. 2023 Dec;120(12):3427-3445. doi: 10.1002/bit.28540. Epub 2023 Aug 28. Biotechnol Bioeng. 2023. PMID: 37638646 Review.

8

Structural-guided design to improve the catalytic performance of aldo-keto reductase KdAKR.

Dai C, Cao HX, Tian JX, Gao YC, Liu HT, Xu SY, Wang YJ, Zheng YG. Dai C, et al. Among authors: xu sy. Biotechnol Bioeng. 2023 Dec;120(12):3543-3556. doi: 10.1002/bit.28535. Epub 2023 Aug 29. Biotechnol Bioeng. 2023. PMID: 37641876

9

Computer-directed rational design enhanced the thermostability of carbonyl reductase LsCR for the synthesis of ticagrelor precursor.

Xu SY, Chu RL, Liu HT, Weng CY, Wang YJ, Zheng YG. Xu SY, et al. Biotechnol Bioeng. 2024 May;121(5):1532-1542. doi: 10.1002/bit.28662. Epub 2024 Jan 24. Biotechnol Bioeng. 2024. PMID: 38265115

10

Tailoring pullulanase PulAR from Anoxybacillus sp. AR-29 for enhanced catalytic performance by a structure-guided consensus approach.

Li SF, Xu SY, Wang YJ, Zheng YG. Li SF, et al. Among authors: xu sy. Bioresour Bioprocess. 2022 Mar 21;9(1):25. doi: 10.1186/s40643-022-00516-4. Bioresour Bioprocess. 2022. PMID: 38647800 Free PMC article.

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