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Nucleosome density shapes kilobase-scale regulation by a mammalian chromatin remodeler.
Abdulhay NJ, Hsieh LJ, McNally CP, Ostrowski MS, Moore CM, Ketavarapu M, Kasinathan S, Nanda AS, Wu K, Chio US, Zhou Z, Goodarzi H, Narlikar GJ, Ramani V. Abdulhay NJ, et al. Among authors: chio us. Nat Struct Mol Biol. 2023 Oct;30(10):1571-1581. doi: 10.1038/s41594-023-01093-6. Epub 2023 Sep 11. Nat Struct Mol Biol. 2023. PMID: 37696956 Free PMC article.
Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Chio US, Palovcak E, Autzen AAA, Autzen HE, Muñoz EN, Yu Z, Wang F, Agard DA, Armache JP, Narlikar GJ, Cheng Y. Chio US, et al. bioRxiv [Preprint]. 2023 Jun 20:2023.06.20.545796. doi: 10.1101/2023.06.20.545796. bioRxiv. 2023. Update in: Nat Commun. 2024 Mar 12;15(1):2225. doi: 10.1038/s41467-024-46178-y PMID: 37546986 Free PMC article. Updated. Preprint.
Cryo-EM structure of the human Sirtuin 6-nucleosome complex.
Chio US, Rechiche O, Bryll AR, Zhu J, Leith EM, Feldman JL, Peterson CL, Tan S, Armache JP. Chio US, et al. Sci Adv. 2023 Apr 14;9(15):eadf7586. doi: 10.1126/sciadv.adf7586. Epub 2023 Apr 14. Sci Adv. 2023. PMID: 37058572 Free PMC article.
Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps.
Remesh SG, Merz GE, Brilot AF, Chio US, Rizo AN, Pospiech TH Jr, Lui I, Laurie MT, Glasgow J, Le CQ, Zhang Y, Diwanji D, Hernandez E, Lopez J, Mehmood H, Pawar KI, Pourmal S, Smith AM, Zhou F; QCRG Structural Biology Consortium; DeRisi J, Kortemme T, Rosenberg OS, Glasgow A, Leung KK, Wells JA, Verba KA. Remesh SG, et al. Among authors: chio us. Structure. 2023 Mar 2;31(3):253-264.e6. doi: 10.1016/j.str.2023.01.009. Epub 2023 Feb 17. Structure. 2023. PMID: 36805129 Free PMC article.
24 results