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21 results

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RAR Inhibitors Display Photo-Protective and Anti-Inflammatory Effects in A2E Stimulated RPE Cells In Vitro through Non-Specific Modulation of PPAR or RXR Transactivation.
Fontaine V, Boumedine T, Monteiro E, Fournié M, Gersende G, Sahel JA, Picaud S, Veillet S, Lafont R, Latil M, Dilda PJ, Camelo S. Fontaine V, et al. Among authors: veillet s. Int J Mol Sci. 2024 Mar 6;25(5):3037. doi: 10.3390/ijms25053037. Int J Mol Sci. 2024. PMID: 38474284 Free PMC article.
Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease.
Fontaine V, Monteiro E, Fournié M, Brazhnikova E, Boumedine T, Vidal C, Balducci C, Guibout L, Latil M, Dilda PJ, Veillet S, Sahel JA, Lafont R, Camelo S. Fontaine V, et al. Among authors: veillet s. Aging (Albany NY). 2020 Apr 7;12(7):6151-6171. doi: 10.18632/aging.103014. Epub 2020 Apr 7. Aging (Albany NY). 2020. PMID: 32255762 Free PMC article.
Testing the efficacy and safety of BIO101, for the prevention of respiratory deterioration, in patients with COVID-19 pneumonia (COVA study): a structured summary of a study protocol for a randomised controlled trial.
Dioh W, Chabane M, Tourette C, Azbekyan A, Morelot-Panzini C, Hajjar LA, Lins M, Nair GB, Whitehouse T, Mariani J, Latil M, Camelo S, Lafont R, Dilda PJ, Veillet S, Agus S. Dioh W, et al. Among authors: veillet s. Trials. 2021 Jan 11;22(1):42. doi: 10.1186/s13063-020-04998-5. Trials. 2021. PMID: 33430924 Free PMC article.
A2E-induced inflammation and angiogenesis in RPE cells in vitro are modulated by PPAR-α, -β/δ, -γ, and RXR antagonists and by norbixin.
Fontaine V, Fournié M, Monteiro E, Boumedine T, Balducci C, Guibout L, Latil M, Sahel JA, Veillet S, Dilda PJ, Lafont R, Camelo S. Fontaine V, et al. Among authors: veillet s. Aging (Albany NY). 2021 Sep 20;13(18):22040-22058. doi: 10.18632/aging.203558. Epub 2021 Sep 20. Aging (Albany NY). 2021. PMID: 34544906 Free PMC article.
21 results