Sun Y - Search Results

1

Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation.

Zhong Y, Xu J, Zhou R, Tang L, Ding S, Ren Z, Song N, Hu B, Yang H, Sun Y, Cheng M, Li J, Liu Y. Zhong Y, et al. Among authors: sun y. J Med Chem. 2024 Mar 28;67(6):4739-4756. doi: 10.1021/acs.jmedchem.3c02329. Epub 2024 Mar 15. J Med Chem. 2024. PMID: 38488882

2

Alpinia hainanensis Rhizome Extract Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis: Active Ingredient Investigation and Evaluation.

Ji KL, Wu MZ, Huang CY, GongPan PC, Sun P, Sun YL, Li J, Xiao CF, Xu YK, Fan QF, Hu HB, Song QS. Ji KL, et al. J Agric Food Chem. 2022 Apr 6;70(13):3989-3999. doi: 10.1021/acs.jafc.1c08038. Epub 2022 Mar 23. J Agric Food Chem. 2022. PMID: 35321548

3

Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation.

Xu Y, Ye X, Zhou Y, Cao X, Peng S, Peng Y, Zhang X, Sun Y, Jiang H, Huang W, Lian H, Yang J, Li J, Ye J. Xu Y, et al. Among authors: sun y. Front Med. 2023 Apr;17(2):339-351. doi: 10.1007/s11684-022-0943-0. Epub 2023 Jan 5. Front Med. 2023. PMID: 36602721

4

Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease.

Li Y, Xu T, Zhao Y, Zhang H, Liu Z, Wang H, Huang C, Shu Z, Gao L, Xie R, Jiao T, Zhang D, Zhang D, Liang X, Zang Y, Sun Y, Liu H, Li J, Zhou Y. Li Y, et al. Among authors: sun y. J Med Chem. 2024 Apr 11;67(7):5642-5661. doi: 10.1021/acs.jmedchem.3c02304. Epub 2024 Mar 28. J Med Chem. 2024. PMID: 38547240

5

Discovery of novel CDK9 inhibitor with tridentate ligand: Design, synthesis and biological evaluation.

Zhong Y, Xu J, Ding S, Cao H, Zhang Y, Hu B, Han S, Yang H, Cheng M, Li J, Sun Y, Liu Y. Zhong Y, et al. Among authors: sun y. Bioorg Chem. 2024 Sep;150:107550. doi: 10.1016/j.bioorg.2024.107550. Epub 2024 Jun 10. Bioorg Chem. 2024. PMID: 38878756

6

The First Discovery of Marine Polyoxygenated Cembranolides as Potential Agents for the Treatment of Ulcerative Colitis.

Cui YY, Jin Y, Sun RN, Wang X, Gao CL, Cui XY, Chen KX, Sun YL, Guo YW, Li J, Li XW. Cui YY, et al. Among authors: sun rn, sun yl. J Med Chem. 2024 Jul 25;67(14):12248-12260. doi: 10.1021/acs.jmedchem.4c00950. Epub 2024 Jul 3. J Med Chem. 2024. PMID: 38959374

7

Identification and structural insight of an effective PPARγ modulator with improved therapeutic index for anti-diabetic drug discovery.

Jiang H, Zhou XE, Shi J, Zhou Z, Zhao G, Zhang X, Sun Y, Suino-Powell K, Ma L, Gao H, Yu X, Li J, Li J, Melcher K, Xu HE, Yi W. Jiang H, et al. Among authors: sun y. Chem Sci. 2020 Jan 21;11(8):2260-2268. doi: 10.1039/c9sc05487a. eCollection 2020 Feb 28. Chem Sci. 2020. PMID: 32190280 Free PMC article.

8

Hedyorienoids A and B, Two Sesquiterpenoid Dimers Featuring Different Polycyclic Skeletons from Hedyosmum orientale.

Fan YY, Sun YL, Zhou B, Zhao JX, Sheng L, Li JY, Yue JM. Fan YY, et al. Org Lett. 2018 Sep 7;20(17):5435-5438. doi: 10.1021/acs.orglett.8b02340. Epub 2018 Aug 16. Org Lett. 2018. PMID: 30113174

9

Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes.

Sun Z, Wang L, Li L, Sun Y, Zhang D, Zhou S, Li Y, Li X, Qiao H, Cui Q, Lan Z, Meng X, Xu J, Geng Y, Dai Y. Sun Z, et al. Among authors: sun y. J Struct Biol. 2023 Sep;215(3):107996. doi: 10.1016/j.jsb.2023.107996. Epub 2023 Jul 5. J Struct Biol. 2023. PMID: 37419228

10

The sphingosine-1-phosphate analogue, FTY-720, promotes the proliferation of embryonic neural stem cells, enhances hippocampal neurogenesis and learning and memory abilities in adult mice.

Sun Y, Hong F, Zhang L, Feng L. Sun Y, et al. Br J Pharmacol. 2016 Sep;173(18):2793-807. doi: 10.1111/bph.13557. Epub 2016 Aug 11. Br J Pharmacol. 2016. PMID: 27429358 Free PMC article.

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