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Page 1
Integration of ζ-deficient CARs into the CD3ζ gene conveys potent cytotoxicity in T and NK cells.
Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, Stein M, Zittel T, Schulenberg S, Porter CE, Andersch L, Künkele A, Alcaniz J, Hoffmann J, Abken H, Abou-El-Enein M, Pruß A, Suzuki M, Cathomen T, Stripecke R, Volk HD, Reinke P, Schmueck-Henneresse M, Wagner DL. Kath J, et al. Among authors: stripecke r. Blood. 2024 Jun 20;143(25):2599-2611. doi: 10.1182/blood.2023020973. Blood. 2024. PMID: 38493479 Free PMC article.
Non-viral TRAC-knocked-in CD19KICAR-T and gp350KICAR-T cells tested against Burkitt lymphomas with type 1 or 2 EBV infection: In vivo cellular dynamics and potency.
Braun T, Pruene A, Darguzyte M, Vom Stein AF, Nguyen PH, Wagner DL, Kath J, Roig-Merino A, Heuser M, Riehm LL, Schneider A, Awerkiew S, Talbot SR, Bleich A, Figueiredo C, Bornhäuser M, Stripecke R. Braun T, et al. Among authors: stripecke r. Front Immunol. 2023 Mar 24;14:1086433. doi: 10.3389/fimmu.2023.1086433. eCollection 2023. Front Immunol. 2023. PMID: 37033919 Free PMC article.
Long-Term Human Immune Reconstitution, T-Cell Development, and Immune Reactivity in Mice Lacking the Murine Major Histocompatibility Complex: Validation with Cellular and Gene Expression Profiles.
Darguzyte M, Antczak P, Bachurski D, Hoelker P, Abedpour N, Gholamipoorfard R, Schlößer HA, Wennhold K, Thelen M, Garcia-Marquez MA, Koenig J, Schneider A, Braun T, Klawonn F, Damrat M, Rahman M, Kleid JM, Theobald SJ, Bauer E, von Kaisenberg C, Talbot SR, Shultz LD, Soper B, Stripecke R. Darguzyte M, et al. Among authors: stripecke r. Cells. 2024 Oct 12;13(20):1686. doi: 10.3390/cells13201686. Cells. 2024. PMID: 39451205 Free PMC article.
Engineered HCMV-infected APCs enable the identification of new immunodominant HLA-restricted epitopes of anti-HCMV T-cell immunity.
Santamorena MM, Tischer-Zimmermann S, Bonifacius A, Mireisz CN, Costa B, Khan F, Kulkarni U, Lauruschkat CD, Sampaio KL, Stripecke R, Blasczyk R, Maecker-Kolhoff B, Kraus S, Schlosser A, Cicin-Sain L, Kalinke U, Eiz-Vesper B. Santamorena MM, et al. Among authors: stripecke r. HLA. 2024 Jun;103(6):e15541. doi: 10.1111/tan.15541. HLA. 2024. PMID: 38923358
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells.
Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, Stein M, Zittel T, Schulenberg S, Porter CE, Andersch L, Künkele A, Alcaniz J, Hoffmann J, Abken H, Abou-El-Enein M, Pruß A, Suzuki M, Cathomen T, Stripecke R, Volk HD, Reinke P, Schmueck-Henneresse M, Wagner DL. Kath J, et al. Among authors: stripecke r. bioRxiv [Preprint]. 2023 Nov 14:2023.11.10.565518. doi: 10.1101/2023.11.10.565518. bioRxiv. 2023. Update in: Blood. 2024 Jun 20;143(25):2599-2611. doi: 10.1182/blood.2023020973 PMID: 38116030 Free PMC article. Updated. Preprint.
Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells.
Kath J, Du W, Pruene A, Braun T, Thommandru B, Turk R, Sturgeon ML, Kurgan GL, Amini L, Stein M, Zittel T, Martini S, Ostendorf L, Wilhelm A, Akyüz L, Rehm A, Höpken UE, Pruß A, Künkele A, Jacobi AM, Volk HD, Schmueck-Henneresse M, Stripecke R, Reinke P, Wagner DL. Kath J, et al. Among authors: stripecke r. Mol Ther Methods Clin Dev. 2022 Apr 12;25:311-330. doi: 10.1016/j.omtm.2022.03.018. eCollection 2022 Jun 9. Mol Ther Methods Clin Dev. 2022. PMID: 35573047 Free PMC article.
In Vivo Lentiviral Gene Delivery of HLA-DR and Vaccination of Humanized Mice for Improving the Human T and B Cell Immune Reconstitution.
Kumar S, Koenig J, Schneider A, Wermeling F, Boddul S, Theobald SJ, Vollmer M, Kloos D, Lachmann N, Klawonn F, Lienenklaus S, Talbot SR, Bleich A, Wenzel N, von Kaisenberg C, Keck J, Stripecke R. Kumar S, et al. Among authors: stripecke r. Biomedicines. 2021 Aug 5;9(8):961. doi: 10.3390/biomedicines9080961. Biomedicines. 2021. PMID: 34440166 Free PMC article.
81 results