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Page 1
Design of amyloidogenic peptide traps.
Sahtoe DD, Andrzejewska EA, Han HL, Rennella E, Schneider MM, Meisl G, Ahlrichs M, Decarreau J, Nguyen H, Kang A, Levine P, Lamb M, Li X, Bera AK, Kay LE, Knowles TPJ, Baker D. Sahtoe DD, et al. Among authors: kay le. Nat Chem Biol. 2024 Aug;20(8):981-990. doi: 10.1038/s41589-024-01578-5. Epub 2024 Mar 19. Nat Chem Biol. 2024. PMID: 38503834 Free PMC article.
Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson's disease.
Nim S, O'Hara DM, Corbi-Verge C, Perez-Riba A, Fujisawa K, Kapadia M, Chau H, Albanese F, Pawar G, De Snoo ML, Ngana SG, Kim J, El-Agnaf OMA, Rennella E, Kay LE, Kalia SK, Kalia LV, Kim PM. Nim S, et al. Among authors: kay le. Nat Commun. 2023 Apr 19;14(1):2150. doi: 10.1038/s41467-023-37464-2. Nat Commun. 2023. PMID: 37076542 Free PMC article.
Dynamic conformational equilibria in the active states of KRAS and NRAS.
Rennella E, Henry C, Dickson CJ, Georgescauld F, Wales TE, Erdmann D, Cotesta S, Maira M, Sedrani R, Brachmann SM, Ostermann N, Engen JR, Kay LE, Beyer KS, Wilcken R, Jahnke W. Rennella E, et al. Among authors: kay le. RSC Chem Biol. 2024 Nov 25;6(1):106-118. doi: 10.1039/d4cb00233d. eCollection 2025 Jan 2. RSC Chem Biol. 2024. PMID: 39664928 Free PMC article.
451 results