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103 results

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Page 1
Towards a general-purpose foundation model for computational pathology.
Chen RJ, Ding T, Lu MY, Williamson DFK, Jaume G, Song AH, Chen B, Zhang A, Shao D, Shaban M, Williams M, Oldenburg L, Weishaupt LL, Wang JJ, Vaidya A, Le LP, Gerber G, Sahai S, Williams W, Mahmood F. Chen RJ, et al. Among authors: le lp. Nat Med. 2024 Mar;30(3):850-862. doi: 10.1038/s41591-024-02857-3. Epub 2024 Mar 19. Nat Med. 2024. PMID: 38504018 Free PMC article.
A General-Purpose Self-Supervised Model for Computational Pathology.
Chen RJ, Ding T, Lu MY, Williamson DFK, Jaume G, Chen B, Zhang A, Shao D, Song AH, Shaban M, Williams M, Vaidya A, Sahai S, Oldenburg L, Weishaupt LL, Wang JJ, Williams W, Le LP, Gerber G, Mahmood F. Chen RJ, et al. Among authors: le lp. ArXiv [Preprint]. 2023 Aug 29:arXiv:2308.15474v1. ArXiv. 2023. PMID: 37693180 Free PMC article. Preprint.
A visual-language foundation model for computational pathology.
Lu MY, Chen B, Williamson DFK, Chen RJ, Liang I, Ding T, Jaume G, Odintsov I, Le LP, Gerber G, Parwani AV, Zhang A, Mahmood F. Lu MY, et al. Among authors: le lp. Nat Med. 2024 Mar;30(3):863-874. doi: 10.1038/s41591-024-02856-4. Epub 2024 Mar 19. Nat Med. 2024. PMID: 38504017 Free PMC article.
A multimodal generative AI copilot for human pathology.
Lu MY, Chen B, Williamson DFK, Chen RJ, Zhao M, Chow AK, Ikemura K, Kim A, Pouli D, Patel A, Soliman A, Chen C, Ding T, Wang JJ, Gerber G, Liang I, Le LP, Parwani AV, Weishaupt LL, Mahmood F. Lu MY, et al. Among authors: le lp. Nature. 2024 Oct;634(8033):466-473. doi: 10.1038/s41586-024-07618-3. Epub 2024 Jun 12. Nature. 2024. PMID: 38866050 Free PMC article.
AI-driven Discovery of Morphomolecular Signatures in Toxicology.
Jaume G, Peeters T, Song AH, Pettit R, Williamson DFK, Oldenburg L, Vaidya A, de Brot S, Chen RJ, Thiran JP, Le LP, Gerber G, Mahmood F. Jaume G, et al. Among authors: le lp. bioRxiv [Preprint]. 2024 Jul 23:2024.07.19.604355. doi: 10.1101/2024.07.19.604355. bioRxiv. 2024. PMID: 39091765 Free PMC article. Preprint.
Deep Learning-based Modeling for Preclinical Drug Safety Assessment.
Jaume G, de Brot S, Song AH, Williamson DFK, Oldenburg L, Zhang A, Chen RJ, Asin J, Blatter S, Dettwiler M, Goepfert C, Grau-Roma L, Soto S, Keller SM, Rottenberg S, Del-Pozo J, Pettit R, Le LP, Mahmood F. Jaume G, et al. Among authors: le lp. bioRxiv [Preprint]. 2024 Jul 23:2024.07.20.604430. doi: 10.1101/2024.07.20.604430. bioRxiv. 2024. PMID: 39091793 Free PMC article. Preprint.
FGFR Alterations in Thyroid Carcinoma: A Novel Class of Primary Drivers with Significant Therapeutic Implications and Secondary Molecular Events Potentially Mediating Resistance in Thyroid Malignancy.
Sabbagh MF, Janovitz T, Dias-Santagata D, Siegmund S, Nardi V, Wirth LJ, Randolph GW, Lennerz JK, Decker B, Nose V, Alzumaili BA, Faquin WC, Barletta JA, Le LP, Iafrate AJ, Sadow PM, Fisch AS. Sabbagh MF, et al. Among authors: le lp. Thyroid. 2024 Sep;34(9):1137-1149. doi: 10.1089/thy.2024.0216. Epub 2024 Aug 7. Thyroid. 2024. PMID: 39003525
Integrated Radiology, Pathology, and Pharmacy Program to Accelerate Access to Osimertinib.
Dagogo-Jack I, Manoogian A, Jessop N, Georgantas NZ, Fintelmann FJ, Farahani A, Digumarthy SR, Price MC, Folch EE, Keyes CM, Do A, Peterson JL, Mino-Kenudson M, Pitman M, Rivera M, Nardi V, Dias-Santagata D, Le LP, Iafrate AJ, Heist RS, Ritterhouse LR, Lennerz JK. Dagogo-Jack I, et al. Among authors: le lp. JCO Oncol Pract. 2023 Sep;19(9):786-792. doi: 10.1200/OP.23.00031. Epub 2023 Jul 12. JCO Oncol Pract. 2023. PMID: 37437226 Free PMC article.
Identification of fusions with potential clinical significance in melanoma.
Moran JMT, Le LP, Nardi V, Golas J, Farahani AA, Signorelli S, Onozato ML, Foreman RK, Duncan LM, Lawrence DP, Lennerz JK, Dias-Santagata D, Hoang MP. Moran JMT, et al. Among authors: le lp. Mod Pathol. 2022 Dec;35(12):1837-1847. doi: 10.1038/s41379-022-01138-z. Epub 2022 Jul 23. Mod Pathol. 2022. PMID: 35871080 Free article.
Implementation and Clinical Adoption of Precision Oncology Workflows Across a Healthcare Network.
Dias-Santagata D, Heist RS, Bard AZ, da Silva AFL, Dagogo-Jack I, Nardi V, Ritterhouse LL, Spring LM, Jessop N, Farahani AA, Mino-Kenudson M, Allen J, Goyal L, Parikh A, Misdraji J, Shankar G, Jordan JT, Martinez-Lage M, Frosch M, Graubert T, Fathi AT, Hobbs GS, Hasserjian RP, Raje N, Abramson J, Schwartz JH, Sullivan RJ, Miller D, Hoang MP, Isakoff S, Ly A, Bouberhan S, Watkins J, Oliva E, Wirth L, Sadow PM, Faquin W, Cote GM, Hung YP, Gao X, Wu CL, Garg S, Rivera M, Le LP, John Iafrate A, Juric D, Hochberg EP, Clark J, Bardia A, Lennerz JK. Dias-Santagata D, et al. Among authors: le lp. Oncologist. 2022 Nov 3;27(11):930-939. doi: 10.1093/oncolo/oyac134. Oncologist. 2022. PMID: 35852437 Free PMC article.
103 results