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Page 1
Primary biliary cholangitis drug evaluation and regulatory approval: Where do we go from here?
Jones DEJ, Beuers U, Bonder A, Carbone M, Culver E, Dyson J, Gish RG, Hansen BE, Hirschfield G, Jones R, Kowdley K, Kremer AE, Lindor K, Mayo M, Mells G, Neuberger J, Prince M, Swain M, Tanaka A, Thorburn D, Trauner M, Trivedi P, Weltman M, Yeoman A, Levy C. Jones DEJ, et al. Hepatology. 2024 Nov 1;80(5):1291-1300. doi: 10.1097/HEP.0000000000000864. Epub 2024 Mar 22. Hepatology. 2024. PMID: 38506926 Free PMC article.
Open-label, clinical trial extension: Two-year safety and efficacy results of seladelpar in patients with primary biliary cholangitis.
Mayo MJ, Vierling JM, Bowlus CL, Levy C, Hirschfield GM, Neff GW, Galambos MR, Gordon SC, Borg BB, Harrison SA, Thuluvath PJ, Goel A, Shiffman ML, Swain MG, Jones DEJ, Trivedi P, Kremer AE, Aspinall RJ, Sheridan DA, Dörffel Y, Yang K, Choi YJ, McWherter CA. Mayo MJ, et al. Among authors: jones dej. Aliment Pharmacol Ther. 2024 Jan;59(2):186-200. doi: 10.1111/apt.17755. Epub 2023 Oct 30. Aliment Pharmacol Ther. 2024. PMID: 37904314
Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study.
Hirschfield GM, Shiffman ML, Gulamhusein A, Kowdley KV, Vierling JM, Levy C, Kremer AE, Zigmond E, Andreone P, Gordon SC, Bowlus CL, Lawitz EJ, Aspinall RJ, Pratt DS, Raikhelson K, Gonzalez-Huezo MS, Heneghan MA, Jeong SH, Ladrón de Guevara AL, Mayo MJ, Dalekos GN, Drenth JPH, Janczewska E, Leggett BA, Nevens F, Vargas V, Zuckerman E, Corpechot C, Fassio E, Hinrichsen H, Invernizzi P, Trivedi PJ, Forman L, Jones DEJ, Ryder SD, Swain MG, Steinberg A, Boudes PF, Choi YJ, McWherter CA; ENHANCE Study Group*. Hirschfield GM, et al. Among authors: jones dej. Hepatology. 2023 Aug 1;78(2):397-415. doi: 10.1097/HEP.0000000000000395. Epub 2023 Apr 6. Hepatology. 2023. PMID: 37386786 Free PMC article. Clinical Trial.
Neurosteroid Activation of GABA-A Receptors: A Potential Treatment Target for Symptoms in Primary Biliary Cholangitis?
Wetten A, Ogle L, Mells G, Hegade VS, Jopson L, Corrigan M, Palmer J, Johansson M, Bäckström T, Doverskog M, Jones DEJ, Dyson JK. Wetten A, et al. Among authors: jones dej. Can J Gastroenterol Hepatol. 2022 Dec 6;2022:3618090. doi: 10.1155/2022/3618090. eCollection 2022. Can J Gastroenterol Hepatol. 2022. PMID: 36523650 Free PMC article.
Anti-Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct-Ligated Mice.
Gee LMV, Barron-Millar B, Leslie J, Richardson C, Zaki MYW, Luli S, Burgoyne RA, Cameron RIT, Smith GR, Brain JG, Innes B, Jopson L, Dyson JK, McKay KRC, Pechlivanis A, Holmes E, Berlinguer-Palmini R, Victorelli S, Mells GF, Sandford RN, Palmer J, Kirby JA, Kiourtis C, Mokochinski J, Hall Z, Bird TG, Borthwick LA, Morris CM, Hanson PS, Jurk D, Stoll EA, LeBeau FEN, Jones DEJ, Oakley F. Gee LMV, et al. Among authors: jones dej. Am J Pathol. 2023 Jan;193(1):11-26. doi: 10.1016/j.ajpath.2022.09.005. Epub 2022 Oct 13. Am J Pathol. 2023. PMID: 36243043 Free article.
The relationship between disease activity and UDCA response criteria in primary biliary cholangitis: A cohort study.
Jones DEJ, Wetten A, Barron-Millar B, Ogle L, Mells G, Flack S, Sandford R, Kirby J, Palmer J, Brotherston S, Jopson L, Brain J, Smith GR, Rushton S, Jones R, Rushbrook S, Thorburn D, Ryder SD, Hirschfield G; UK-PBC Research Consortium; Dyson JK. Jones DEJ, et al. EBioMedicine. 2022 Jun;80:104068. doi: 10.1016/j.ebiom.2022.104068. Epub 2022 May 21. EBioMedicine. 2022. PMID: 35609437 Free PMC article.
153 results