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Page 1
Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
Arunagiri A, Alam M, Haataja L, Draz H, Alasad B, Samy P, Sadique N, Tong Y, Cai Y, Shakeri H, Fantuzzi F, Ibrahim H, Jang I, Sidarala V, Soleimanpour SA, Satin LS, Otonkoski T, Cnop M, Itkin-Ansari P, Kaufman RJ, Liu M, Arvan P. Arunagiri A, et al. Protein Sci. 2024 Apr;33(4):e4949. doi: 10.1002/pro.4949. Protein Sci. 2024. PMID: 38511500 Free PMC article.
Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction.
Yeh YT, Sona C, Yan X, Li Y, Pathak A, McDermott MI, Xie Z, Liu L, Arunagiri A, Wang Y, Cazenave-Gassiot A, Ghosh A, von Meyenn F, Kumarasamy S, Najjar SM, Jia S, Wenk MR, Traynor-Kaplan A, Arvan P, Barg S, Bankaitis VA, Poy MN. Yeh YT, et al. Among authors: arunagiri a. Nat Commun. 2023 Jul 17;14(1):4250. doi: 10.1038/s41467-023-39978-1. Nat Commun. 2023. PMID: 37460527 Free PMC article.
Nutrient-dependent regulation of β-cell proinsulin content.
Xu X, Arunagiri A, Alam M, Haataja L, Evans CR, Zhao I, Castro-Gutierrez R, Russ HA, Demangel C, Qi L, Tsai B, Liu M, Arvan P. Xu X, et al. Among authors: arunagiri a. J Biol Chem. 2023 Jul;299(7):104836. doi: 10.1016/j.jbc.2023.104836. Epub 2023 May 19. J Biol Chem. 2023. PMID: 37209827 Free PMC article.
Editorial: Molecular determinants of protein assemblies in health and disease.
Kroschwald S, Arunagiri A, Ventura S, Ranganathan S, Kohler V. Kroschwald S, et al. Among authors: arunagiri a. Front Mol Biosci. 2022 Dec 14;9:1107686. doi: 10.3389/fmolb.2022.1107686. eCollection 2022. Front Mol Biosci. 2022. PMID: 36589240 Free PMC article. No abstract available.
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
Xu X, Arunagiri A, Haataja L, Alam M, Ji S, Qi L, Tsai B, Liu M, Arvan P. Xu X, et al. Among authors: arunagiri a. J Biol Chem. 2022 Oct;298(10):102406. doi: 10.1016/j.jbc.2022.102406. Epub 2022 Aug 19. J Biol Chem. 2022. PMID: 35988641 Free PMC article.
The G209R mutant mouse as a model for human PCSK1 polyendocrinopathy.
Shakya M, Gahlot S, Martin NK, Arunagiri A, Martin MG, Arvan P, Low MJ, Lindberg I. Shakya M, et al. Among authors: arunagiri a. Endocrinology. 2022 Mar 4;163(5):bqac024. doi: 10.1210/endocr/bqac024. Online ahead of print. Endocrinology. 2022. PMID: 35245347 Free PMC article.
27 results