Willis CL - Search Results

1

The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis.

Devine AJ, Parnell AE, Back CR, Lees NR, Johns ST, Zulkepli AZ, Barringer R, Zorn K, Stach JEM, Crump MP, Hayes MA, van der Kamp MW, Race PR, Willis CL. Devine AJ, et al. Among authors: willis cl. Angew Chem Weinheim Bergstr Ger. 2023 Jan 16;135(3):e202213053. doi: 10.1002/ange.202213053. Epub 2022 Dec 8. Angew Chem Weinheim Bergstr Ger. 2023. PMID: 38516347 Free PMC article.

2

Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens.

Wu J, Cooper SM, Cox RJ, Crosby J, Crump MP, Hothersall J, Simpson TJ, Thomas CM, Willis CL. Wu J, et al. Among authors: willis cl. Chem Commun (Camb). 2007 May 28;(20):2040-2. doi: 10.1039/b700613f. Chem Commun (Camb). 2007. PMID: 17713071

3

Probing the Interactions of early polyketide intermediates with the Actinorhodin ACP from S. coelicolor A3(2).

Evans SE, Williams C, Arthur CJ, Płoskoń E, Wattana-amorn P, Cox RJ, Crosby J, Willis CL, Simpson TJ, Crump MP. Evans SE, et al. Among authors: willis cl. J Mol Biol. 2009 Jun 12;389(3):511-28. doi: 10.1016/j.jmb.2009.03.072. Epub 2009 Apr 8. J Mol Biol. 2009. PMID: 19361520

4

Recognition of intermediate functionality by acyl carrier protein over a complete cycle of fatty acid biosynthesis.

Płoskoń E, Arthur CJ, Kanari AL, Wattana-amorn P, Williams C, Crosby J, Simpson TJ, Willis CL, Crump MP. Płoskoń E, et al. Among authors: willis cl. Chem Biol. 2010 Jul 30;17(7):776-85. doi: 10.1016/j.chembiol.2010.05.024. Chem Biol. 2010. PMID: 20659690

5

Biosynthesis of mupirocin by Pseudomonas fluorescens NCIMB 10586 involves parallel pathways.

Gao SS, Hothersall J, Wu J, Murphy AC, Song Z, Stephens ER, Thomas CM, Crump MP, Cox RJ, Simpson TJ, Willis CL. Gao SS, et al. Among authors: willis cl. J Am Chem Soc. 2014 Apr 9;136(14):5501-7. doi: 10.1021/ja501731p. Epub 2014 Mar 27. J Am Chem Soc. 2014. PMID: 24625190

6

The Catalytic Mechanism of a Natural Diels-Alderase Revealed in Molecular Detail.

Byrne MJ, Lees NR, Han LC, van der Kamp MW, Mulholland AJ, Stach JE, Willis CL, Race PR. Byrne MJ, et al. Among authors: willis cl. J Am Chem Soc. 2016 May 18;138(19):6095-8. doi: 10.1021/jacs.6b00232. Epub 2016 May 6. J Am Chem Soc. 2016. PMID: 27140661

7

Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics.

Gao SS, Wang L, Song Z, Hothersall J, Stevens ER, Connolly J, Winn PJ, Cox RJ, Crump MP, Race PR, Thomas CM, Simpson TJ, Willis CL. Gao SS, et al. Among authors: willis cl. Angew Chem Int Ed Engl. 2017 Mar 27;56(14):3930-3934. doi: 10.1002/anie.201611590. Epub 2017 Feb 9. Angew Chem Int Ed Engl. 2017. PMID: 28181382

8

Recognition of extended linear and cyclised polyketide mimics by a type II acyl carrier protein.

Dong X, Bailey CD, Williams C, Crosby J, Simpson TJ, Willis CL, Crump MP. Dong X, et al. Among authors: willis cl. Chem Sci. 2016 Mar 1;7(3):1779-1785. doi: 10.1039/c5sc03864b. Epub 2015 Dec 10. Chem Sci. 2016. PMID: 28936328 Free PMC article.

9

Elucidation of the relative and absolute stereochemistry of the kalimantacin/batumin antibiotics.

Thistlethwaite IRG, Bull FM, Cui C, Walker PD, Gao SS, Wang L, Song Z, Masschelein J, Lavigne R, Crump MP, Race PR, Simpson TJ, Willis CL. Thistlethwaite IRG, et al. Among authors: willis cl. Chem Sci. 2017 Sep 1;8(9):6196-6201. doi: 10.1039/c7sc01670k. Epub 2017 Jul 11. Chem Sci. 2017. PMID: 28989652 Free PMC article.

10

Fine Tuning of Antibiotic Activity by a Tailoring Hydroxylase in a Trans-AT Polyketide Synthase Pathway.

Mohammad HH, Connolly JA, Song Z, Hothersall J, Race PR, Willis CL, Simpson TJ, Winn PJ, Thomas CM. Mohammad HH, et al. Among authors: willis cl. Chembiochem. 2018 Apr 16;19(8):836-841. doi: 10.1002/cbic.201800036. Epub 2018 Mar 13. Chembiochem. 2018. PMID: 29363252

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