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Page 1
Small-molecule inhibition of SARS-CoV-2 NSP14 RNA cap methyltransferase.
Meyer C, Garzia A, Miller MW, Huggins DJ, Myers RW, Hoffmann HH, Ashbrook AW, Jannath SY, Liverton N, Kargman S, Zimmerman M, Nelson AM, Sharma V, Dolgov E, Cangialosi J, Penalva-Lopez S, Alvarez N, Chang CW, Oswal N, Gonzalez I, Rasheed R, Goldgirsh K, Davis JA, Ramos-Espiritu L, Menezes MR, Larson C, Nitsche J, Ganichkin O, Alwaseem H, Molina H, Steinbacher S, Glickman JF, Perlin DS, Rice CM, Meinke PT, Tuschl T. Meyer C, et al. Among authors: alwaseem h. Nature. 2024 Dec 11. doi: 10.1038/s41586-024-08320-0. Online ahead of print. Nature. 2024. PMID: 39663451
Glycosphingolipid synthesis mediates immune evasion in KRAS-driven cancer.
Soula M, Unlu G, Welch R, Chudnovskiy A, Uygur B, Shah V, Alwaseem H, Bunk P, Subramanyam V, Yeh HW, Khan A, Heissel S, Goodarzi H, Victora GD, Beyaz S, Birsoy K. Soula M, et al. Among authors: alwaseem h. Nature. 2024 Sep;633(8029):451-458. doi: 10.1038/s41586-024-07787-1. Epub 2024 Aug 7. Nature. 2024. PMID: 39112706
Threonine fuels glioblastoma through YRDC-mediated codon-biased translational reprogramming.
Wu X, Yuan H, Wu Q, Gao Y, Duan T, Yang K, Huang T, Wang S, Yuan F, Lee D, Taori S, Plute T, Heissel S, Alwaseem H, Isay-Del Viscio M, Molina H, Agnihotri S, Hsu DJ, Zhang N, Rich JN. Wu X, et al. Among authors: alwaseem h. Nat Cancer. 2024 Jul;5(7):1024-1044. doi: 10.1038/s43018-024-00748-7. Epub 2024 Mar 22. Nat Cancer. 2024. PMID: 38519786
Autoregulatory control of mitochondrial glutathione homeostasis.
Liu Y, Liu S, Tomar A, Yen FS, Unlu G, Ropek N, Weber RA, Wang Y, Khan A, Gad M, Peng J, Terzi E, Alwaseem H, Pagano AE, Heissel S, Molina H, Allwein B, Kenny TC, Possemato RL, Zhao L, Hite RK, Vinogradova EV, Mansy SS, Birsoy K. Liu Y, et al. Among authors: alwaseem h. Science. 2023 Nov 17;382(6672):820-828. doi: 10.1126/science.adf4154. Epub 2023 Nov 2. Science. 2023. PMID: 37917749 Free PMC article.
Disruption of proteome by an oncogenic fusion kinase alters metabolism in fibrolamellar hepatocellular carcinoma.
Levin SN, Tomasini MD, Knox J, Shirani M, Shebl B, Requena D, Clark J, Heissel S, Alwaseem H, Surjan R, Lahasky R, Molina H, Torbenson MS, Lyons B, Migler RD, Coffino P, Simon SM. Levin SN, et al. Among authors: alwaseem h. Sci Adv. 2023 Jun 23;9(25):eadg7038. doi: 10.1126/sciadv.adg7038. Epub 2023 Jun 21. Sci Adv. 2023. PMID: 37343102 Free PMC article.
Arginine limitation causes a directed DNA sequence evolution response in colorectal cancer cells.
Hsu DJ, Gao J, Yamaguchi N, Pinzaru A, Mandayam N, Liberti M, Heissel S, Alwaseem H, Tavazoie S, Tavazoie SF. Hsu DJ, et al. Among authors: alwaseem h. bioRxiv [Preprint]. 2023 Jan 2:2023.01.02.521806. doi: 10.1101/2023.01.02.521806. bioRxiv. 2023. Update in: Sci Adv. 2023 Jan 6;9(1):eade9120. doi: 10.1126/sciadv.ade9120 PMID: 36711568 Free PMC article. Updated. Preprint.
31 results