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Cytokeratin-18 is a sensitive biomarker of alanine transaminase increase in a placebo-controlled, randomized, crossover trial of therapeutic paracetamol dosing (PATH-BP biomarker substudy).
Scullion KM, MacIntyre IM, Sloan-Dennison S, Clark B, Fineran P, Mair J, Creasey D, Rathmell C, Faulds K, Graham D, Webb DJ, Dear JW. Scullion KM, et al. Among authors: rathmell c. Toxicol Sci. 2024 May 28;199(2):203-209. doi: 10.1093/toxsci/kfae031. Toxicol Sci. 2024. PMID: 38521541 Free PMC article. Clinical Trial.