Smith CIE - Search Results

1

Reduced clone size upon BTK inhibitor resistance mutations relates to toxicity caused by inherited PLCG2 gain-of-function variations.

Smith CIE, Zain R. Smith CIE, et al. Eur J Haematol. 2024 Jul;113(1):130-131. doi: 10.1111/ejh.14204. Epub 2024 Mar 26. Eur J Haematol. 2024. PMID: 38529725 No abstract available.

2

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA.

Moreno PM, Geny S, Pabon YV, Bergquist H, Zaghloul EM, Rocha CS, Oprea II, Bestas B, Andaloussi SE, Jørgensen PT, Pedersen EB, Lundin KE, Zain R, Wengel J, Smith CI. Moreno PM, et al. Nucleic Acids Res. 2013 Mar 1;41(5):3257-73. doi: 10.1093/nar/gkt007. Epub 2013 Jan 23. Nucleic Acids Res. 2013. PMID: 23345620 Free PMC article.

3

Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes.

Geny S, Moreno PM, Krzywkowski T, Gissberg O, Andersen NK, Isse AJ, El-Madani AM, Lou C, Pabon YV, Anderson BA, Zaghloul EM, Zain R, Hrdlicka PJ, Jørgensen PT, Nilsson M, Lundin KE, Pedersen EB, Wengel J, Smith CI. Geny S, et al. Nucleic Acids Res. 2016 Mar 18;44(5):2007-19. doi: 10.1093/nar/gkw021. Epub 2016 Feb 8. Nucleic Acids Res. 2016. PMID: 26857548 Free PMC article.

4

Delivery, Effect on Cell Viability, and Plasticity of Modified Aptamer Constructs.

Gissberg O, Zaghloul EM, Lundin KE, Nguyen CH, Landras-Guetta C, Wengel J, Zain R, Smith CI. Gissberg O, et al. Nucleic Acid Ther. 2016 Jun;26(3):183-9. doi: 10.1089/nat.2015.0592. Epub 2016 Feb 9. Nucleic Acid Ther. 2016. PMID: 26859550

5

Four Novel Splice-Switch Reporter Cell Lines: Distinct Impact of Oligonucleotide Chemistry and Delivery Vector on Biological Activity.

Rocha CS, Lundin KE, Behlke MA, Zain R, El Andaloussi S, Smith CI. Rocha CS, et al. Nucleic Acid Ther. 2016 Dec;26(6):381-391. doi: 10.1089/nat.2016.0631. Epub 2016 Sep 15. Nucleic Acid Ther. 2016. PMID: 27629437

6

Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting.

Bergquist H, Rocha CS, Álvarez-Asencio R, Nguyen CH, Rutland MW, Smith CI, Good L, Nielsen PE, Zain R. Bergquist H, et al. PLoS One. 2016 Nov 15;11(11):e0165788. doi: 10.1371/journal.pone.0165788. eCollection 2016. PLoS One. 2016. PMID: 27846236 Free PMC article.

7

CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression.

Zaghloul EM, Gissberg O, Moreno PMD, Siggens L, Hällbrink M, Jørgensen AS, Ekwall K, Zain R, Wengel J, Lundin KE, Smith CIE. Zaghloul EM, et al. Among authors: smith cie. Nucleic Acids Res. 2017 May 19;45(9):5153-5169. doi: 10.1093/nar/gkx111. Nucleic Acids Res. 2017. PMID: 28334749 Free PMC article.

8

LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures.

Pabon-Martinez YV, Xu Y, Villa A, Lundin KE, Geny S, Nguyen CH, Pedersen EB, Jørgensen PT, Wengel J, Nilsson L, Smith CIE, Zain R. Pabon-Martinez YV, et al. Among authors: smith cie. Sci Rep. 2017 Sep 8;7(1):11043. doi: 10.1038/s41598-017-09147-8. Sci Rep. 2017. PMID: 28887512 Free PMC article.

9

Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides: In Silico and in Vitro Studies.

Hartono YD, Pabon-Martinez YV, Uyar A, Wengel J, Lundin KE, Zain R, Smith CIE, Nilsson L, Villa A. Hartono YD, et al. Among authors: smith cie. ACS Omega. 2017 May 31;2(5):2165-2177. doi: 10.1021/acsomega.7b00347. Epub 2017 May 17. ACS Omega. 2017. PMID: 30023656 Free PMC article.

10

Novel peptide-dendrimer/lipid/oligonucleotide ternary complexes for efficient cellular uptake and improved splice-switching activity.

Saher O, Rocha CSJ, Zaghloul EM, Wiklander OPB, Zamolo S, Heitz M, Ezzat K, Gupta D, Reymond JL, Zain R, Hollfelder F, Darbre T, Lundin KE, El Andaloussi S, Smith CIE. Saher O, et al. Among authors: smith cie. Eur J Pharm Biopharm. 2018 Nov;132:29-40. doi: 10.1016/j.ejpb.2018.09.002. Epub 2018 Sep 4. Eur J Pharm Biopharm. 2018. PMID: 30193928

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