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Comparing deep learning and pathologist quantification of cell-level PD-L1 expression in non-small cell lung cancer whole-slide images.
van Eekelen L, Spronck J, Looijen-Salamon M, Vos S, Munari E, Girolami I, Eccher A, Acs B, Boyaci C, de Souza GS, Demirel-Andishmand M, Meesters LD, Zegers D, van der Woude L, Theelen W, van den Heuvel M, Grünberg K, van Ginneken B, van der Laak J, Ciompi F. van Eekelen L, et al. Among authors: van der woude l, van ginneken b, van der laak j, van den heuvel m. Sci Rep. 2024 Mar 26;14(1):7136. doi: 10.1038/s41598-024-57067-1. Sci Rep. 2024. PMID: 38531958 Free PMC article.
FGFR1, 2 and 3 protein overexpression and molecular aberrations of FGFR3 in early stage non-small cell lung cancer.
Theelen WS, Mittempergher L, Willems SM, Bosma AJ, Peters DD, van der Noort V, Japenga EJ, Peeters T, Koole K, Šuštić T, Blaauwgeers JL, van Noesel CJ, Bernards R, van den Heuvel MM. Theelen WS, et al. Among authors: van noesel cj, van den heuvel mm, van der noort v. J Pathol Clin Res. 2016 Aug 13;2(4):223-233. doi: 10.1002/cjp2.51. eCollection 2016 Oct. J Pathol Clin Res. 2016. PMID: 27785367 Free PMC article.
First-Line Nivolumab in Stage IV or Recurrent Non-Small-Cell Lung Cancer.
Carbone DP, Reck M, Paz-Ares L, Creelan B, Horn L, Steins M, Felip E, van den Heuvel MM, Ciuleanu TE, Badin F, Ready N, Hiltermann TJN, Nair S, Juergens R, Peters S, Minenza E, Wrangle JM, Rodriguez-Abreu D, Borghaei H, Blumenschein GR Jr, Villaruz LC, Havel L, Krejci J, Corral Jaime J, Chang H, Geese WJ, Bhagavatheeswaran P, Chen AC, Socinski MA; CheckMate 026 Investigators. Carbone DP, et al. Among authors: van den heuvel mm. N Engl J Med. 2017 Jun 22;376(25):2415-2426. doi: 10.1056/NEJMoa1613493. N Engl J Med. 2017. PMID: 28636851 Free PMC article.
Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indicate impaired IFNγ signaling in non-small cell lung cancer.
Theelen WSME, Kuilman T, Schulze K, Zou W, Krijgsman O, Peters DDGC, Cornelissen S, Monkhorst K, Sarma P, Sumiyoshi T, Amler LC, Willems SM, Blaauwgeers JLG, van Noesel CJM, Peeper DS, van den Heuvel MM, Kowanetz M. Theelen WSME, et al. Among authors: van den heuvel mm, van noesel cjm. PLoS One. 2019 May 24;14(5):e0216864. doi: 10.1371/journal.pone.0216864. eCollection 2019. PLoS One. 2019. PMID: 31125352 Free PMC article.
Prediction of response to anti-PD-1 therapy in patients with non-small-cell lung cancer by electronic nose analysis of exhaled breath.
de Vries R, Muller M, van der Noort V, Theelen WSME, Schouten RD, Hummelink K, Muller SH, Wolf-Lansdorf M, Dagelet JWF, Monkhorst K, Maitland-van der Zee AH, Baas P, Sterk PJ, van den Heuvel MM. de Vries R, et al. Among authors: van den heuvel mm, van der noort v. Ann Oncol. 2019 Oct 1;30(10):1660-1666. doi: 10.1093/annonc/mdz279. Ann Oncol. 2019. PMID: 31529107 Free article.
Evaluation of a Hybrid Capture-Based Pan-Cancer Panel for Analysis of Treatment Stratifying Oncogenic Aberrations and Processes.
Kroeze LI, de Voer RM, Kamping EJ, von Rhein D, Jansen EAM, Hermsen MJW, Barberis MCP, Botling J, Garrido-Martin EM, Haller F, Lacroix L, Maes B, Merkelbach-Bruse S, Pestinger V, Pfarr N, Stenzinger A, van den Heuvel MM, Grünberg K, Ligtenberg MJL. Kroeze LI, et al. Among authors: van den heuvel mm. J Mol Diagn. 2020 Jun;22(6):757-769. doi: 10.1016/j.jmoldx.2020.02.009. Epub 2020 Mar 20. J Mol Diagn. 2020. PMID: 32205293 Free article.
880 results