Kwan JS - Search Results

1

Liver-specific adiponectin gene therapy suppresses microglial NLRP3-inflammasome activation for treating Alzheimer's disease.

Ng RC, Jian M, Ma OK, Xiang AW, Bunting M, Kwan JS, Wong CW, Yick LW, Chung SK, Lam KS, Alexander IE, Xu A, Chan KH. Ng RC, et al. Among authors: kwan js. J Neuroinflammation. 2024 Mar 27;21(1):77. doi: 10.1186/s12974-024-03066-y. J Neuroinflammation. 2024. PMID: 38539253 Free PMC article.

2

Chronic adiponectin deficiency leads to Alzheimer's disease-like cognitive impairments and pathologies through AMPK inactivation and cerebral insulin resistance in aged mice.

Ng RC, Cheng OY, Jian M, Kwan JS, Ho PW, Cheng KK, Yeung PK, Zhou LL, Hoo RL, Chung SK, Xu A, Lam KS, Chan KH. Ng RC, et al. Among authors: kwan js. Mol Neurodegener. 2016 Nov 25;11(1):71. doi: 10.1186/s13024-016-0136-x. Mol Neurodegener. 2016. PMID: 27884163 Free PMC article.

3

Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling pathway.

Jian M, Kwan JS, Bunting M, Ng RC, Chan KH. Jian M, et al. Among authors: kwan js. J Neuroinflammation. 2019 May 25;16(1):110. doi: 10.1186/s12974-019-1492-6. J Neuroinflammation. 2019. PMID: 31128596 Free PMC article.

4

Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer's disease mouse model.

Ng RC, Jian M, Ma OK, Bunting M, Kwan JS, Zhou GJ, Senthilkumar K, Iyaswamy A, Chan PK, Li M, Leung KM, Kumar Durairajan SS, Lam KS, Chu LW, Festenstein R, Chung SK, Chan KH. Ng RC, et al. Among authors: kwan js. Mol Psychiatry. 2021 Oct;26(10):5669-5689. doi: 10.1038/s41380-020-0701-0. Epub 2020 Mar 4. Mol Psychiatry. 2021. PMID: 32132650

5

Memantine ameliorates motor impairments and pathologies in a mouse model of neuromyelitis optica spectrum disorders.

Yick LW, Tang CH, Ma OK, Kwan JS, Chan KH. Yick LW, et al. Among authors: kwan js. J Neuroinflammation. 2020 Aug 11;17(1):236. doi: 10.1186/s12974-020-01913-2. J Neuroinflammation. 2020. PMID: 32782018 Free PMC article.

6

Adiponectin is protective against oxidative stress induced cytotoxicity in amyloid-beta neurotoxicity.

Chan KH, Lam KS, Cheng OY, Kwan JS, Ho PW, Cheng KK, Chung SK, Ho JW, Guo VY, Xu A. Chan KH, et al. Among authors: kwan js. PLoS One. 2012;7(12):e52354. doi: 10.1371/journal.pone.0052354. Epub 2012 Dec 27. PLoS One. 2012. PMID: 23300647 Free PMC article.

7

Aquaporin-4 Autoantibodies From Neuromyelitis Optica Spectrum Disorder Patients Induce Complement-Independent Immunopathologies in Mice.

Yick LW, Ma OK, Ng RC, Kwan JS, Chan KH. Yick LW, et al. Among authors: kwan js. Front Immunol. 2018 Jun 25;9:1438. doi: 10.3389/fimmu.2018.01438. eCollection 2018. Front Immunol. 2018. PMID: 29988553 Free PMC article.

8

T follicular helper cells contribute to pathophysiology in a model of neuromyelitis optica spectrum disorders.

Yick LW, Ma OK, Chan EY, Yau KX, Kwan JS, Chan KH. Yick LW, et al. Among authors: kwan js. JCI Insight. 2023 Feb 22;8(4):e161003. doi: 10.1172/jci.insight.161003. JCI Insight. 2023. PMID: 36649074 Free PMC article.

9

The molecular history of IDH-mutant astrocytomas without adjuvant treatment.

Shi ZF, Li KK, Kwan JS, Chung NY, Wong SC, Chu AW, Chen H, Chan DT, Mao Y, Ng HK. Shi ZF, et al. Among authors: kwan js. Brain Pathol. 2024 Oct 30:e13300. doi: 10.1111/bpa.13300. Online ahead of print. Brain Pathol. 2024. PMID: 39473241

10

Combined Quantitative amyloid-β PET and Structural MRI Features Improve Alzheimer's Disease Classification in Random Forest Model - A Multicenter Study.

Bao YW, Wang ZJ, Shea YF, Chiu PK, Kwan JS, Chan FH, Mak HK. Bao YW, et al. Among authors: kwan js. Acad Radiol. 2024 Dec;31(12):5154-5163. doi: 10.1016/j.acra.2024.06.040. Epub 2024 Jul 12. Acad Radiol. 2024. PMID: 39003227 Free article.

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