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Endothelial-Specific Reduction in Arf6 Impairs Insulin-Stimulated Vasodilation and Skeletal Muscle Blood Flow Resulting in Systemic Insulin Resistance in Mice.
Islam MT, Cai J, Allen S, Moreno DG, Bloom SI, Bramwell RC, Mitton J, Horn AG, Zhu W, Donato AJ, Holland WL, Lesniewski LA. Islam MT, et al. Among authors: lesniewski la. Arterioscler Thromb Vasc Biol. 2024 May;44(5):1101-1113. doi: 10.1161/ATVBAHA.123.319375. Epub 2024 Mar 28. Arterioscler Thromb Vasc Biol. 2024. PMID: 38545783
Cellular and molecular biology of aging endothelial cells.
Donato AJ, Morgan RG, Walker AE, Lesniewski LA. Donato AJ, et al. Among authors: lesniewski la. J Mol Cell Cardiol. 2015 Dec;89(Pt B):122-35. doi: 10.1016/j.yjmcc.2015.01.021. Epub 2015 Feb 2. J Mol Cell Cardiol. 2015. PMID: 25655936 Free PMC article. Review.
Advanced age results in a diminished endothelial glycocalyx.
Machin DR, Bloom SI, Campbell RA, Phuong TTT, Gates PE, Lesniewski LA, Rondina MT, Donato AJ. Machin DR, et al. Among authors: lesniewski la. Am J Physiol Heart Circ Physiol. 2018 Sep 1;315(3):H531-H539. doi: 10.1152/ajpheart.00104.2018. Epub 2018 May 11. Am J Physiol Heart Circ Physiol. 2018. PMID: 29750566 Free PMC article.
T lymphocyte depletion ameliorates age-related metabolic impairments in mice.
Trott DW, Islam MT, Buckley DJ, Donato AJ, Dutson T, Sorensen ES, Cai J, Gogulamudi VR, Phuong TTT, Lesniewski LA. Trott DW, et al. Among authors: lesniewski la. Geroscience. 2021 Jun;43(3):1331-1347. doi: 10.1007/s11357-021-00368-4. Epub 2021 Apr 24. Geroscience. 2021. PMID: 33893902 Free PMC article.
T cells mediate cell non-autonomous arterial ageing in mice.
Trott DW, Machin DR, Phuong TTT, Adeyemo AO, Bloom SI, Bramwell RC, Sorensen ES, Lesniewski LA, Donato AJ. Trott DW, et al. Among authors: lesniewski la. J Physiol. 2021 Aug;599(16):3973-3991. doi: 10.1113/JP281698. J Physiol. 2021. PMID: 34164826 Free PMC article.
Mechanisms and consequences of endothelial cell senescence.
Bloom SI, Islam MT, Lesniewski LA, Donato AJ. Bloom SI, et al. Among authors: lesniewski la. Nat Rev Cardiol. 2023 Jan;20(1):38-51. doi: 10.1038/s41569-022-00739-0. Epub 2022 Jul 19. Nat Rev Cardiol. 2023. PMID: 35853997 Free PMC article. Review.
73 results