Nguyen K - Search Results

1

The sounds of silencing: dynamic epigenetic control of HIV latency.

Nguyen K, Karn J. Nguyen K, et al. Curr Opin HIV AIDS. 2024 May 1;19(3):102-109. doi: 10.1097/COH.0000000000000850. Epub 2024 Mar 12. Curr Opin HIV AIDS. 2024. PMID: 38547337 Free PMC article. Review.

2

Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency.

Nguyen K, Das B, Dobrowolski C, Karn J. Nguyen K, et al. mBio. 2017 Feb 28;8(1):e00133-17. doi: 10.1128/mBio.00133-17. mBio. 2017. PMID: 28246360 Free PMC article.

3

Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation.

Nguyen K, Dobrowolski C, Shukla M, Cho WK, Luttge B, Karn J. Nguyen K, et al. PLoS Pathog. 2021 Oct 21;17(10):e1010014. doi: 10.1371/journal.ppat.1010014. eCollection 2021 Oct. PLoS Pathog. 2021. PMID: 34673825 Free PMC article.

4

A Structurally Conserved RNA Element within SARS-CoV-2 ORF1a RNA and S mRNA Regulates Translation in Response to Viral S Protein-Induced Signaling in Human Lung Cells.

Basu A, Penumutchu S, Nguyen K, Mbonye U, Tolbert BS, Karn J, Komar AA, Mazumder B. Basu A, et al. Among authors: nguyen k. J Virol. 2022 Jan 26;96(2):e0167821. doi: 10.1128/JVI.01678-21. Epub 2021 Nov 10. J Virol. 2022. PMID: 34757848 Free PMC article.

5

A Reliable Primary Cell Model for HIV Latency: The QUECEL (Quiescent Effector Cell Latency) Method.

Shukla M, Kizito F, Mbonye U, Nguyen K, Dobrowolski C, Karn J. Shukla M, et al. Among authors: nguyen k. Methods Mol Biol. 2022;2407:57-68. doi: 10.1007/978-1-0716-1871-4_5. Methods Mol Biol. 2022. PMID: 34985657

6

Recruitment of the CoREST transcription repressor complexes by Nerve Growth factor IB-like receptor (Nurr1/NR4A2) mediates silencing of HIV in microglial cells.

Ye F, Alvarez-Carbonell D, Nguyen K, Leskov K, Garcia-Mesa Y, Sreeram S, Valadkhan S, Karn J. Ye F, et al. Among authors: nguyen k. PLoS Pathog. 2022 Jul 7;18(7):e1010110. doi: 10.1371/journal.ppat.1010110. eCollection 2022 Jul. PLoS Pathog. 2022. PMID: 35797416 Free PMC article.

7

The potential role of HIV-1 latency in promoting neuroinflammation and HIV-1-associated neurocognitive disorder.

Sreeram S, Ye F, Garcia-Mesa Y, Nguyen K, El Sayed A, Leskov K, Karn J. Sreeram S, et al. Among authors: nguyen k. Trends Immunol. 2022 Aug;43(8):630-639. doi: 10.1016/j.it.2022.06.003. Epub 2022 Jul 12. Trends Immunol. 2022. PMID: 35840529 Free PMC article. Review.

8

COVID-19 plasma exosomes promote proinflammatory immune responses in peripheral blood mononuclear cells.

Chen L, Chen R, Yao M, Feng Z, Yuan G, Ye F, Nguyen K, Karn J, McComsey GA, McIntyre TM, Jin G. Chen L, et al. Among authors: nguyen k. Sci Rep. 2022 Dec 16;12(1):21779. doi: 10.1038/s41598-022-26457-8. Sci Rep. 2022. PMID: 36526691 Free PMC article.

9

A viral pan-end RNA element and host complex define a SARS-CoV-2 regulon.

Khan D, Terenzi F, Liu G, Ghosh PK, Ye F, Nguyen K, China A, Ramachandiran I, Chakraborty S, Stefan J, Khan K, Vasu K, Dong F, Willard B, Karn J, Gack MU, Fox PL. Khan D, et al. Among authors: nguyen k. Nat Commun. 2023 Jun 9;14(1):3385. doi: 10.1038/s41467-023-39091-3. Nat Commun. 2023. PMID: 37296097 Free PMC article.

10

Structural rearrangements in the nucleus localize latent HIV proviruses to a perinucleolar compartment supportive of reactivation.

Kizito F, Nguyen K, Mbonye U, Shukla M, Luttge B, Checkley MA, Agaponova A, Leskov K, Karn J. Kizito F, et al. Among authors: nguyen k. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2202003121. doi: 10.1073/pnas.2202003121. Epub 2024 Apr 26. Proc Natl Acad Sci U S A. 2024. PMID: 38669184 Free PMC article.

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