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Page 1
Discovery of Novel Macrocyclic MERTK/AXL Dual Inhibitors.
Kong D, Tian Q, Chen Z, Zheng H, Stashko MA, Yan D, Earp HS, Frye SV, DeRyckere D, Kireev D, Graham DK, Wang X. Kong D, et al. Among authors: earp hs. J Med Chem. 2024 Apr 11;67(7):5866-5882. doi: 10.1021/acs.jmedchem.4c00148. Epub 2024 Mar 31. J Med Chem. 2024. PMID: 38556760
MERTK inhibition selectively activates a DC - T-cell axis to provide anti-leukemia immunity.
Huelse JM, Bhasin SS, Jacobsen KM, Yim J, Thomas BE, Branella GM, Bakhtiari M, Chimenti ML, Baxter TA, Raikar SS, Wang X, Frye SV, Henry CJ, Earp HS, Bhasin M, DeRyckere D, Graham DK. Huelse JM, et al. Among authors: earp hs. Leukemia. 2024 Dec;38(12):2685-2698. doi: 10.1038/s41375-024-02408-2. Epub 2024 Sep 25. Leukemia. 2024. PMID: 39322710
Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome.
East MP, Sprung RW, Okumu DO, Olivares-Quintero JF, Joisa CU, Chen X, Zhang Q, Erdmann-Gilmore P, Mi Y, Sciaky N, Malone JP, Bhatia S, McCabe IC, Xu Y, Sutcliffe MD, Luo J, Spears PA, Perou CM, Earp HS, Carey LA, Yeh JJ, Spector DL, Gomez SM, Spanheimer PM, Townsend RR, Johnson GL. East MP, et al. Among authors: earp hs. bioRxiv [Preprint]. 2024 Oct 4:2024.10.04.614143. doi: 10.1101/2024.10.04.614143. bioRxiv. 2024. PMID: 39464086 Free PMC article. Preprint.
221 results