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Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy.
Saecker RM, Mueller AU, Malone B, Chen J, Budell WC, Dandey VP, Maruthi K, Mendez JH, Molina N, Eng ET, Yen LY, Potter CS, Carragher B, Darst SA. Saecker RM, et al. Among authors: darst sa. bioRxiv [Preprint]. 2024 Mar 14:2024.03.13.584744. doi: 10.1101/2024.03.13.584744. bioRxiv. 2024. Update in: Nat Struct Mol Biol. 2024 Nov;31(11):1778-1788. doi: 10.1038/s41594-024-01349-9 PMID: 38559232 Free PMC article. Updated. Preprint.
Stepwise Promoter Melting by Bacterial RNA Polymerase.
Chen J, Chiu C, Gopalkrishnan S, Chen AY, Olinares PDB, Saecker RM, Winkelman JT, Maloney MF, Chait BT, Ross W, Gourse RL, Campbell EA, Darst SA. Chen J, et al. Among authors: darst sa. Mol Cell. 2020 Apr 16;78(2):275-288.e6. doi: 10.1016/j.molcel.2020.02.017. Epub 2020 Mar 10. Mol Cell. 2020. PMID: 32160514 Free PMC article.
Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex.
Chen J, Malone B, Llewellyn E, Grasso M, Shelton PMM, Olinares PDB, Maruthi K, Eng E, Vatandaslar H, Chait BT, Kapoor T, Darst SA, Campbell EA. Chen J, et al. Among authors: darst sa. bioRxiv [Preprint]. 2020 Jul 13:2020.07.08.194084. doi: 10.1101/2020.07.08.194084. bioRxiv. 2020. Update in: Cell. 2020 Sep 17;182(6):1560-1573.e13. doi: 10.1016/j.cell.2020.07.033 PMID: 32676607 Free PMC article. Updated. Preprint.
Time-resolved cryo-EM using Spotiton.
Dandey VP, Budell WC, Wei H, Bobe D, Maruthi K, Kopylov M, Eng ET, Kahn PA, Hinshaw JE, Kundu N, Nimigean CM, Fan C, Sukomon N, Darst SA, Saecker RM, Chen J, Malone B, Potter CS, Carragher B. Dandey VP, et al. Among authors: darst sa. Nat Methods. 2020 Sep;17(9):897-900. doi: 10.1038/s41592-020-0925-6. Epub 2020 Aug 10. Nat Methods. 2020. PMID: 32778833 Free PMC article.
172 results