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XELOX (capecitabine plus oxaliplatin) plus bevacizumab (anti-VEGF-A antibody) with or without adoptive cell immunotherapy in the treatment of patients with previously untreated metastatic colorectal cancer: a multicenter, open-label, randomized, controlled, phase 3 trial.
Pan QZ, Zhao JJ, Liu L, Zhang DS, Wang LP, Hu WW, Weng DS, Xu X, Li YZ, Tang Y, Zhang WH, Li JY, Zheng X, Wang QJ, Li YQ, Xiang T, Zhou L, Yang SN, Wu C, Huang RX, He J, Du WJ, Chen LJ, Wu YN, Xu B, Shen Q, Zhang Y, Jiang JT, Ren XB, Xia JC. Pan QZ, et al. Among authors: shen q. Signal Transduct Target Ther. 2024 Apr 3;9(1):79. doi: 10.1038/s41392-024-01788-2. Signal Transduct Target Ther. 2024. PMID: 38565886 Free PMC article. Clinical Trial.
Immunogenicity and safety of two novel human papillomavirus 4- and 9-valent vaccines in Chinese women aged 20-45 years: A randomized, blinded, controlled with Gardasil (type 6/11/16/18), phase III non-inferiority clinical trial.
Shu Y, Yu Y, Ji Y, Zhang L, Li Y, Qin H, Huang Z, Ou Z, Huang M, Shen Q, Li Z, Hu M, Li C, Zhang G, Zhang J. Shu Y, et al. Among authors: shen q. Vaccine. 2022 Nov 15;40(48):6947-6955. doi: 10.1016/j.vaccine.2022.10.022. Epub 2022 Oct 22. Vaccine. 2022. PMID: 36283897 Free article. Clinical Trial.
Cryo-EM reveals cholesterol binding in the lysosomal GPCR-like protein LYCHOS.
Zhao J, Shen Q, Yong X, Li X, Tian X, Sun S, Xu Z, Zhang X, Zhang L, Yang H, Shao Z, Xu H, Jiang Y, Zhang Y, Yan W. Zhao J, et al. Among authors: shen q. Nat Struct Mol Biol. 2025 Jan 17. doi: 10.1038/s41594-024-01470-9. Online ahead of print. Nat Struct Mol Biol. 2025. PMID: 39824976
Proteolysis-targeting influenza vaccine strains induce broad-spectrum immunity and in vivo protection.
Shen J, Li J, Shen Q, Hou J, Zhang C, Bai H, Ai X, Su Y, Wang Z, Zhang Y, Xu B, Hao J, Wang P, Zhang Q, Ye AY, Li Z, Feng T, Li L, Qi F, Wang Q, Sun Y, Liu C, Xi X, Yan L, Hong H, Chen Y, Xie X, Xie J, Liu X, Du R, Plebani R, Zhang L, Zhou D, Church G, Si L. Shen J, et al. Among authors: shen q. Nat Microbiol. 2025 Jan 15. doi: 10.1038/s41564-024-01908-2. Online ahead of print. Nat Microbiol. 2025. PMID: 39815008
PROTAR Vaccine 2.0 generates influenza vaccines by degrading multiple viral proteins.
Zhang C, Hou J, Li Z, Shen Q, Bai H, Chen L, Shen J, Wang P, Su Y, Li J, Zhang Q, Liu C, Xi X, Qi F, Chen Y, Xie X, Ye AY, Liu X, Plebani R, Church G, Si L. Zhang C, et al. Among authors: shen q. Nat Chem Biol. 2025 Jan 15. doi: 10.1038/s41589-024-01813-z. Online ahead of print. Nat Chem Biol. 2025. PMID: 39814992
6,357 results