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Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs.
Villeneuve L, Girard H, Fortier LC, Gagné JF, Guillemette C. Villeneuve L, et al. Among authors: guillemette c. J Pharmacol Exp Ther. 2003 Oct;307(1):117-28. doi: 10.1124/jpet.103.054072. Epub 2003 Aug 27. J Pharmacol Exp Ther. 2003. PMID: 12944498
Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver.
Girard H, Court MH, Bernard O, Fortier LC, Villeneuve L, Hao Q, Greenblatt DJ, von Moltke LL, Perussed L, Guillemette C. Girard H, et al. Among authors: guillemette c. Pharmacogenetics. 2004 Aug;14(8):501-15. doi: 10.1097/01.fpc.0000114754.08559.27. Pharmacogenetics. 2004. PMID: 15284532
Circulating estrogens in endometrial cancer cases and their relationship with tissular expression of key estrogen biosynthesis and metabolic pathways.
Lépine J, Audet-Walsh E, Grégoire J, Têtu B, Plante M, Ménard V, Ayotte P, Brisson J, Caron P, Villeneuve L, Bélanger A, Guillemette C. Lépine J, et al. Among authors: guillemette c. J Clin Endocrinol Metab. 2010 Jun;95(6):2689-98. doi: 10.1210/jc.2010-2648. Epub 2010 Apr 6. J Clin Endocrinol Metab. 2010. PMID: 20371658
203 results