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Poor association between 13-valent pneumococcal conjugate vaccine-induced serum and mucosal antibody responses with experimental Streptococcus pneumoniae serotype 6B colonisation.
Tembo G, Mayuni M, Kamng'ona R, Chimgoneko L, Chiwala G, Sichone S, Galafa B, Thole F, Mkandawire C, Chirwa AE, Nsomba E, Nkhoma V, Ngoliwa C, Toto N, Makhaza L, Muyaya A, Kudowa E, Henrion MYR, Dula D, Morton B, Chikaonda T, Gordon SB, Jambo KC. Tembo G, et al. Among authors: galafa b. Vaccine. 2024 Apr 30;42(12):2975-2982. doi: 10.1016/j.vaccine.2024.03.055. Epub 2024 Apr 4. Vaccine. 2024. PMID: 38570270 Free PMC article.
Effect of 13-valent pneumococcal conjugate vaccine on experimental carriage of Streptococcus pneumoniae serotype 6B in Blantyre, Malawi: a randomised controlled trial and controlled human infection study.
Dula D, Morton B, Chikaonda T, Chirwa AE, Nsomba E, Nkhoma V, Ngoliwa C, Sichone S, Galafa B, Tembo G, Chaponda M, Toto N, Kamng'ona R, Makhaza L, Muyaya A, Thole F, Kudowa E, Howard A, Kenny-Nyazika T, Ndaferankhande J, Mkandawire C, Chiwala G, Chimgoneko L, Banda NPK, Rylance J, Ferreira D, Jambo K, Henrion MYR, Gordon SB; Malawi Accelerated Research in Vaccines, Experimental and Laboratory Systems (MARVELS) consortium. Dula D, et al. Among authors: galafa b. Lancet Microbe. 2023 Sep;4(9):e683-e691. doi: 10.1016/S2666-5247(23)00178-7. Lancet Microbe. 2023. PMID: 37659418 Free PMC article. Clinical Trial.
Natural carriage of Streptococcus pneumoniae is associated with increased experimental pneumococcal carriage but reduced conjugate vaccine efficacy in a human challenge model.
Galafa B, Chikaonda T, Kudowa E, Sichone S, Sibale L, Thole F, Mkandawire C, Dula D, Nsomba E, Tembo G, Chaponda M, Chirwa AE, Nkhoma V, Ngoliwa C, Kamng'ona R, Toto N, Makhaza L, Muyaya A, Howard A, Nyazika TK, Ndaferankhande J, Chimgoneko L, Banda NPK, Chiwala G, Rylance J, Ferreira D, Jambo KC, Morton B, Henrion MYR, Gordon SB. Galafa B, et al. J Infect Dis. 2024 Jul 10:jiae341. doi: 10.1093/infdis/jiae341. Online ahead of print. J Infect Dis. 2024. PMID: 38984706