Essigmann JM - Search Results

1

Stable Interstrand Cross-Links Generated from the Repair of 1,N⁶-Ethenoadenine in DNA by α-Ketoglutarate/Fe(II)-Dependent Dioxygenase ALKBH2.

Wang J, Takyi NA, Hsiao YC, Tang Q, Chen YT, Liu CW, Ma J, Qi R, Bian K, Peng Z, Essigmann JM, Lu K, Wetmore SD, Li D. Wang J, et al. Among authors: essigmann jm. J Am Chem Soc. 2024 Apr 17;146(15):10381-10392. doi: 10.1021/jacs.3c12890. Epub 2024 Apr 4. J Am Chem Soc. 2024. PMID: 38573229 Free PMC article.

2

A rationally designed genotoxin that selectively destroys estrogen receptor-positive breast cancer cells.

Mitra K, Marquis JC, Hillier SM, Rye PT, Zayas B, Lee AS, Essigmann JM, Croy RG. Mitra K, et al. Among authors: essigmann jm. J Am Chem Soc. 2002 Mar 6;124(9):1862-3. doi: 10.1021/ja017344p. J Am Chem Soc. 2002. PMID: 11866593 Free PMC article.

3

Chemical biology of mutagenesis and DNA repair: cellular responses to DNA alkylation.

Shrivastav N, Li D, Essigmann JM. Shrivastav N, et al. Among authors: essigmann jm. Carcinogenesis. 2010 Jan;31(1):59-70. doi: 10.1093/carcin/bgp262. Epub 2009 Oct 29. Carcinogenesis. 2010. PMID: 19875697 Free PMC article. Review.

4

Repair of DNA Alkylation Damage by the Escherichia coli Adaptive Response Protein AlkB as Studied by ESI-TOF Mass Spectrometry.

Li D, Delaney JC, Page CM, Chen AS, Wong C, Drennan CL, Essigmann JM. Li D, et al. Among authors: essigmann jm. J Nucleic Acids. 2010 Oct 27;2010:369434. doi: 10.4061/2010/369434. J Nucleic Acids. 2010. PMID: 21048928 Free PMC article.

5

Exocyclic carbons adjacent to the N6 of adenine are targets for oxidation by the Escherichia coli adaptive response protein AlkB.

Li D, Delaney JC, Page CM, Yang X, Chen AS, Wong C, Drennan CL, Essigmann JM. Li D, et al. Among authors: essigmann jm. J Am Chem Soc. 2012 May 30;134(21):8896-901. doi: 10.1021/ja3010094. Epub 2012 May 21. J Am Chem Soc. 2012. PMID: 22512456 Free PMC article.

6

Removal of N-alkyl modifications from N(2)-alkylguanine and N(4)-alkylcytosine in DNA by the adaptive response protein AlkB.

Li D, Fedeles BI, Shrivastav N, Delaney JC, Yang X, Wong C, Drennan CL, Essigmann JM. Li D, et al. Among authors: essigmann jm. Chem Res Toxicol. 2013 Aug 19;26(8):1182-7. doi: 10.1021/tx400096m. Epub 2013 Jul 10. Chem Res Toxicol. 2013. PMID: 23773213 Free PMC article.

7

Direct observation of multiple tautomers of oxythiamine and their recognition by the thiamine pyrophosphate riboswitch.

Singh V, Peng CS, Li D, Mitra K, Silvestre KJ, Tokmakoff A, Essigmann JM. Singh V, et al. Among authors: essigmann jm. ACS Chem Biol. 2014 Jan 17;9(1):227-36. doi: 10.1021/cb400581f. Epub 2013 Nov 19. ACS Chem Biol. 2014. PMID: 24252063 Free PMC article.

8

A chemical genetics analysis of the roles of bypass polymerase DinB and DNA repair protein AlkB in processing N2-alkylguanine lesions in vivo.

Shrivastav N, Fedeles BI, Li D, Delaney JC, Frick LE, Foti JJ, Walker GC, Essigmann JM. Shrivastav N, et al. Among authors: essigmann jm. PLoS One. 2014 Apr 14;9(4):e94716. doi: 10.1371/journal.pone.0094716. eCollection 2014. PLoS One. 2014. PMID: 24733044 Free PMC article.

9

Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkB.

Singh V, Fedeles BI, Li D, Delaney JC, Kozekov ID, Kozekova A, Marnett LJ, Rizzo CJ, Essigmann JM. Singh V, et al. Among authors: essigmann jm. Chem Res Toxicol. 2014 Sep 15;27(9):1619-31. doi: 10.1021/tx5002817. Epub 2014 Aug 26. Chem Res Toxicol. 2014. PMID: 25157679 Free PMC article.

10

The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond.

Fedeles BI, Singh V, Delaney JC, Li D, Essigmann JM. Fedeles BI, et al. Among authors: essigmann jm. J Biol Chem. 2015 Aug 21;290(34):20734-20742. doi: 10.1074/jbc.R115.656462. Epub 2015 Jul 7. J Biol Chem. 2015. PMID: 26152727 Free PMC article. Review.

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