Randazzo PA - Search Results

1

Point mutations in Arf1 reveal cooperative effects of the N-terminal extension and myristate for GTPase-activating protein catalytic activity.

Rosenberg EM Jr, Jian X, Soubias O, Jackson RA, Gladu E, Andersen E, Esser L, Sodt AJ, Xia D, Byrd RA, Randazzo PA. Rosenberg EM Jr, et al. Among authors: randazzo pa. PLoS One. 2024 Apr 4;19(4):e0295103. doi: 10.1371/journal.pone.0295103. eCollection 2024. PLoS One. 2024. PMID: 38574162 Free PMC article.

2

Functional Expression and Characterization of Human Myristoylated-Arf1 in Nanodisc Membrane Mimetics.

Li Y, Soubias O, Li J, Sun S, Randazzo PA, Byrd RA. Li Y, et al. Among authors: randazzo pa. Biochemistry. 2019 Mar 12;58(10):1423-1431. doi: 10.1021/acs.biochem.8b01323. Epub 2019 Feb 20. Biochemistry. 2019. PMID: 30735034 Free PMC article.

3

Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate.

Roy NS, Jian X, Soubias O, Zhai P, Hall JR, Dagher JN, Coussens NP, Jenkins LM, Luo R, Akpan IO, Hall MD, Byrd RA, Yohe ME, Randazzo PA. Roy NS, et al. Among authors: randazzo pa. J Biol Chem. 2019 Nov 15;294(46):17354-17370. doi: 10.1074/jbc.RA119.009269. Epub 2019 Oct 6. J Biol Chem. 2019. PMID: 31591270 Free PMC article.

4

Membrane surface recognition by the ASAP1 PH domain and consequences for interactions with the small GTPase Arf1.

Soubias O, Pant S, Heinrich F, Zhang Y, Roy NS, Li J, Jian X, Yohe ME, Randazzo PA, Lösche M, Tajkhorshid E, Byrd RA. Soubias O, et al. Among authors: randazzo pa. Sci Adv. 2020 Sep 30;6(40):eabd1882. doi: 10.1126/sciadv.abd1882. Print 2020 Sep. Sci Adv. 2020. PMID: 32998886 Free PMC article.

5

The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins.

Rosenberg EM Jr, Jian X, Soubias O, Yoon HY, Yadav MP, Hammoudeh S, Pallikkuth S, Akpan I, Chen PW, Maity TK, Jenkins LM, Yohe ME, Byrd RA, Randazzo PA. Rosenberg EM Jr, et al. Among authors: randazzo pa. J Biol Chem. 2023 Mar;299(3):102992. doi: 10.1016/j.jbc.2023.102992. Epub 2023 Feb 8. J Biol Chem. 2023. PMID: 36758799 Free PMC article.

6

Modifications to the C-terminus of Arf1 alter cell functions and protein interactions.

Jian X, Cavenagh M, Gruschus JM, Randazzo PA, Kahn RA. Jian X, et al. Among authors: randazzo pa. Traffic. 2010 Jun;11(6):732-42. doi: 10.1111/j.1600-0854.2010.01054.x. Epub 2010 Feb 27. Traffic. 2010. PMID: 20214751 Free PMC article.

7

The importance of seeing surface (effects).

Gruschus JM, Byrd RA, Randazzo PA. Gruschus JM, et al. Among authors: randazzo pa. Structure. 2014 Mar 4;22(3):363-5. doi: 10.1016/j.str.2014.02.005. Structure. 2014. PMID: 24607142 Free PMC article.

8

Quantitative Analysis of Guanine Nucleotide Exchange Factors (GEFs) as Enzymes.

Randazzo PA, Jian X, Chen PW, Zhai P, Soubias O, Northup JK. Randazzo PA, et al. Cell Logist. 2014 Jan 9;3:e27609. doi: 10.4161/cl.27609. eCollection 2013. Cell Logist. 2014. PMID: 25332840 Free PMC article.

9

Simple in vitro assay of Arf GAPs and preparation of Arf proteins as substrates.

Chen PW, Jian X, Luo R, Randazzo PA. Chen PW, et al. Among authors: randazzo pa. Methods Cell Biol. 2015;130:69-80. doi: 10.1016/bs.mcb.2015.03.021. Epub 2015 Jun 11. Methods Cell Biol. 2015. PMID: 26360029 Free PMC article.

10

Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1.

Jian X, Tang WK, Zhai P, Roy NS, Luo R, Gruschus JM, Yohe ME, Chen PW, Li Y, Byrd RA, Xia D, Randazzo PA. Jian X, et al. Among authors: randazzo pa. Structure. 2015 Nov 3;23(11):1977-88. doi: 10.1016/j.str.2015.08.008. Epub 2015 Sep 10. Structure. 2015. PMID: 26365802 Free PMC article.

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