MacLean KN - Search Results

1

Deep postnatal phenotyping of a new mouse model of nonketotic hyperglycinemia.

Swanson MA, Jiang H, Busquet N, Carlsen J, Brindley C, Benke TA, Van Hove RA, Friederich MW, MacLean KN, Mesches MH, Van Hove JLK. Swanson MA, et al. Among authors: maclean kn. bioRxiv [Preprint]. 2024 Mar 29:2024.03.26.586818. doi: 10.1101/2024.03.26.586818. bioRxiv. 2024. Update in: J Inherit Metab Dis. 2024 Sep;47(5):971-990. doi: 10.1002/jimd.12755 PMID: 38586005 Free PMC article. Updated. Preprint.

2

Deep postnatal phenotyping of a new mouse model of nonketotic hyperglycinemia.

Swanson MA, Jiang H, Busquet N, Carlsen J, Brindley C, Benke TA, Van Hove RA, Friederich MW, MacLean KN, Mesches MH, Van Hove JLK. Swanson MA, et al. Among authors: maclean kn. J Inherit Metab Dis. 2024 Sep;47(5):971-990. doi: 10.1002/jimd.12755. Epub 2024 Jun 5. J Inherit Metab Dis. 2024. PMID: 38840294

3

Restoration of the ER stress response protein TDAG51 in hepatocytes mitigates NAFLD in mice.

Yousof TR, Bouchard CC, Alb M, Lynn EG, Lhoták S, Jiang H, MacDonald M, Li H, Byun JH, Makda Y, Athanasopoulos M, Maclean KN, Cherrington NJ, Naqvi A, Igdoura SA, Krepinsky JC, Steinberg GR, Austin RC. Yousof TR, et al. Among authors: maclean kn. J Biol Chem. 2024 Feb;300(2):105655. doi: 10.1016/j.jbc.2024.105655. Epub 2024 Jan 16. J Biol Chem. 2024. PMID: 38237682 Free PMC article.

4

Dysregulation of hepatic one-carbon metabolism in classical homocystinuria: Implications of redox-sensitive DHFR repression and tetrahydrofolate depletion for pathogenesis and treatment.

Maclean KN, Jiang H, Neill PD, Chanin RR, Hurt KJ, Orlicky DJ, Bottiglieri T, Roede JR, Stabler SP. Maclean KN, et al. FASEB J. 2024 Jul 15;38(13):e23795. doi: 10.1096/fj.202302585R. FASEB J. 2024. PMID: 38984928

5

Characterization of mitochondrial and metabolic alterations induced by trisomy 21 during neural differentiation.

Prutton KM, Marentette JO, Maclean KN, Roede JR. Prutton KM, et al. Among authors: maclean kn. Free Radic Biol Med. 2023 Feb 20;196:11-21. doi: 10.1016/j.freeradbiomed.2023.01.009. Epub 2023 Jan 10. Free Radic Biol Med. 2023. PMID: 36638900 Free PMC article.

6

Oxidative stress as a candidate mechanism for accelerated neuroectodermal differentiation due to trisomy 21.

Prutton KM, Marentette JO, Leifheit BA, Esquer H, LaBarbera DV, Anderson CC, Maclean KN, Roede JR. Prutton KM, et al. Among authors: maclean kn. Free Radic Biol Med. 2022 Jun;186:32-42. doi: 10.1016/j.freeradbiomed.2022.04.015. Epub 2022 May 7. Free Radic Biol Med. 2022. PMID: 35537597

7

Trisomy 21 results in modest impacts on mitochondrial function and central carbon metabolism.

Anderson CC, Marentette JO, Prutton KM, Rauniyar AK, Reisz JA, D'Alessandro A, Maclean KN, Saba LM, Roede JR. Anderson CC, et al. Among authors: maclean kn. Free Radic Biol Med. 2021 Aug 20;172:201-212. doi: 10.1016/j.freeradbiomed.2021.06.003. Epub 2021 Jun 12. Free Radic Biol Med. 2021. PMID: 34129926 Free PMC article.

8

Analysis of differential neonatal lethality in cystathionine β-synthase deficient mouse models using metabolic profiling.

Gupta S, Wang L, Slifker MJ, Cai KQ, Maclean KN, Wasek B, Bottiglieri T, Kruger WD. Gupta S, et al. Among authors: maclean kn. FASEB J. 2021 Jun;35(6):e21629. doi: 10.1096/fj.202100302R. FASEB J. 2021. PMID: 33949005 Free PMC article.

9

Cystathionine γ-lyase promotes estrogen-stimulated uterine artery blood flow via glutathione homeostasis.

Bok R, Guerra DD, Lorca RA, Wennersten SA, Harris PS, Rauniyar AK, Stabler SP, MacLean KN, Roede JR, Brown LD, Hurt KJ. Bok R, et al. Among authors: maclean kn. Redox Biol. 2021 Apr;40:101827. doi: 10.1016/j.redox.2020.101827. Epub 2020 Dec 8. Redox Biol. 2021. PMID: 33485059 Free PMC article.

10

Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis.

Maclean KN, Jiang H, Phinney WN, Mclagan BM, Roede JR, Stabler SP. Maclean KN, et al. Mol Genet Metab. 2021 Feb;132(2):128-138. doi: 10.1016/j.ymgme.2021.01.003. Epub 2021 Jan 11. Mol Genet Metab. 2021. PMID: 33483253

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