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Page 1
Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype.
Nuechterlein N, Shelbourn A, Szulzewsky F, Arora S, Casad M, Pattwell S, Merino-Galan L, Sulman E, Arowa S, Alvinez N, Jung M, Brown D, Tang K, Jackson S, Stoica S, Chittaboina P, Banasavadi-Siddegowda YK, Wirsching HG, Stella N, Shapiro L, Paddison P, Patel AP, Gilbert MR, Abdullaev Z, Aldape K, Pratt D, Holland EC, Cimino PJ. Nuechterlein N, et al. Among authors: patel ap. Genes Dev. 2024 Apr 17;38(5-6):273-288. doi: 10.1101/gad.351350.123. Genes Dev. 2024. PMID: 38589034 Free PMC article.
A brave new framework for glioma drug development.
Hotchkiss KM, Karschnia P, Schreck KC, Geurts M, Cloughesy TF, Huse J, Duke ES, Lathia J, Ashley DM, Nduom EK, Long G, Singh K, Chalmers A, Ahluwalia MS, Heimberger A, Bagley S, Todo T, Verhaak R, Kelly PD, Hervey-Jumper S, de Groot J, Patel A, Fecci P, Parney I, Wykes V, Watts C, Burns TC, Sanai N, Preusser M, Tonn JC, Drummond KJ, Platten M, Das S, Tanner K, Vogelbaum MA, Weller M, Whittle JR, Berger MS, Khasraw M. Hotchkiss KM, et al. Lancet Oncol. 2024 Oct;25(10):e512-e519. doi: 10.1016/S1470-2045(24)00190-6. Lancet Oncol. 2024. PMID: 39362262 Review.
Surgical Management and Advances in the Treatment of Glioma.
Hardigan AA, Jackson JD, Patel AP. Hardigan AA, et al. Among authors: patel ap. Semin Neurol. 2023 Dec;43(6):810-824. doi: 10.1055/s-0043-1776766. Epub 2023 Nov 14. Semin Neurol. 2023. PMID: 37963582 Free PMC article. Review.
Genomic Drivers of Coronary Artery Disease and Risk of Future Outcomes After Coronary Angiography.
Supriami K, Urbut SM, Tello-Ayala JR, Unlu O, Friedman SF, Abou-Karam R, Koyama S, Uddin MM, Pomerantsev E, Lu MT, Honigberg MC, Aragam KG, Doshi-Velez F, Patel AP, Natarajan P, Ellinor PT, Fahed AC. Supriami K, et al. Among authors: patel ap. JAMA Netw Open. 2025 Jan 2;8(1):e2455368. doi: 10.1001/jamanetworkopen.2024.55368. JAMA Netw Open. 2025. PMID: 39836422 Free article.
Notes from the Field: Increase in Diagnoses of Human Parvovirus B19-Associated Aplastic Crises in Children and Adolescents with Sickle Cell Disease - Atlanta, Georgia, December 14, 2023-September 30, 2024.
Yee MEM, Kalmus GG, Patel AP, Payne JN, Tang A, Gee BE. Yee MEM, et al. Among authors: patel ap. MMWR Morb Mortal Wkly Rep. 2024 Nov 28;73(47):1090-1091. doi: 10.15585/mmwr.mm7347a5. MMWR Morb Mortal Wkly Rep. 2024. PMID: 39602417 Free PMC article. No abstract available.
245 results