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247 results

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Page 1
Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype.
Nuechterlein N, Shelbourn A, Szulzewsky F, Arora S, Casad M, Pattwell S, Merino-Galan L, Sulman E, Arowa S, Alvinez N, Jung M, Brown D, Tang K, Jackson S, Stoica S, Chittaboina P, Banasavadi-Siddegowda YK, Wirsching HG, Stella N, Shapiro L, Paddison P, Patel AP, Gilbert MR, Abdullaev Z, Aldape K, Pratt D, Holland EC, Cimino PJ. Nuechterlein N, et al. Among authors: sulman e. Genes Dev. 2024 Apr 17;38(5-6):273-288. doi: 10.1101/gad.351350.123. Genes Dev. 2024. PMID: 38589034 Free PMC article.
Multigene sets for clinical application in glioma.
de Groot JF, Sulman EP, Aldape KD. de Groot JF, et al. J Natl Compr Canc Netw. 2011 Apr;9(4):449-56; quiz 457. doi: 10.6004/jnccn.2011.0040. J Natl Compr Canc Netw. 2011. PMID: 21464148
The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma.
Bhat KP, Salazar KL, Balasubramaniyan V, Wani K, Heathcock L, Hollingsworth F, James JD, Gumin J, Diefes KL, Kim SH, Turski A, Azodi Y, Yang Y, Doucette T, Colman H, Sulman EP, Lang FF, Rao G, Copray S, Vaillant BD, Aldape KD. Bhat KP, et al. Genes Dev. 2011 Dec 15;25(24):2594-609. doi: 10.1101/gad.176800.111. Genes Dev. 2011. PMID: 22190458 Free PMC article.
Molecular biology of brain tumors.
Li J, Sulman E, Aldape K. Li J, et al. Among authors: sulman e. Handb Clin Neurol. 2012;104:23-34. doi: 10.1016/B978-0-444-52138-5.00002-5. Handb Clin Neurol. 2012. PMID: 22230432 Review.
A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival.
Zheng S, Fu J, Vegesna R, Mao Y, Heathcock LE, Torres-Garcia W, Ezhilarasan R, Wang S, McKenna A, Chin L, Brennan CW, Yung WK, Weinstein JN, Aldape KD, Sulman EP, Chen K, Koul D, Verhaak RG. Zheng S, et al. Among authors: sulman ep. Genes Dev. 2013 Jul 1;27(13):1462-72. doi: 10.1101/gad.213686.113. Epub 2013 Jun 24. Genes Dev. 2013. PMID: 23796897 Free PMC article.
Bevacizumab for newly diagnosed glioblastoma.
Gilbert MR, Sulman EP, Mehta MP. Gilbert MR, et al. N Engl J Med. 2014 May 22;370(21):2048-9. doi: 10.1056/NEJMc1403303. N Engl J Med. 2014. PMID: 24849088 No abstract available.
MerTK as a therapeutic target in glioblastoma.
Wu J, Frady LN, Bash RE, Cohen SM, Schorzman AN, Su YT, Irvin DM, Zamboni WC, Wang X, Frye SV, Ewend MG, Sulman EP, Gilbert MR, Earp HS, Miller CR. Wu J, et al. Among authors: sulman ep. Neuro Oncol. 2018 Jan 10;20(1):92-102. doi: 10.1093/neuonc/nox111. Neuro Oncol. 2018. PMID: 28605477 Free PMC article.
Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma.
Maraka S, Groves MD, Mammoser AG, Melguizo-Gavilanes I, Conrad CA, Tremont-Lukats IW, Loghin ME, O'Brien BJ, Puduvalli VK, Sulman EP, Hess KR, Aldape KD, Gilbert MR, de Groot JF, Alfred Yung WK, Penas-Prado M. Maraka S, et al. Among authors: sulman ep. Cancer. 2019 Feb 1;125(3):424-433. doi: 10.1002/cncr.31811. Epub 2018 Oct 25. Cancer. 2019. PMID: 30359477 Free PMC article. Clinical Trial.
247 results