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Myeloid-T cell interplay and cell state transitions associated with checkpoint inhibitor response in melanoma.
Schlenker R, Schwalie PC, Dettling S, Huesser T, Irmisch A, Mariani M, Martínez Gómez JM, Ribeiro A, Limani F, Herter S, Yángüez E, Hoves S, Somandin J, Siebourg-Polster J, Kam-Thong T, de Matos IG, Umana P, Dummer R, Levesque MP, Bacac M. Schlenker R, et al. Among authors: dummer r. Med. 2024 Jul 12;5(7):759-779.e7. doi: 10.1016/j.medj.2024.03.015. Epub 2024 Apr 8. Med. 2024. PMID: 38593812 Free article.
Immune signatures predict development of autoimmune toxicity in patients with cancer treated with immune checkpoint inhibitors.
Nuñez NG, Berner F, Friebel E, Unger S, Wyss N, Gomez JM, Purde MT, Niederer R, Porsch M, Lichtensteiger C, Kramer R, Erdmann M, Schmitt C, Heinzerling L, Abdou MT, Karbach J, Schadendorf D, Zimmer L, Ugurel S, Klümper N, Hölzel M, Power L, Kreutmair S, Capone M, Madonna G, Cevhertas L, Heider A, Amaral T, Hasan Ali O, Bomze D, Dimitriou F, Diem S, Ascierto PA, Dummer R, Jäger E, Driessen C, Levesque MP, van de Veen W, Joerger M, Früh M, Becher B, Flatz L. Nuñez NG, et al. Among authors: dummer r. Med. 2023 Feb 10;4(2):113-129.e7. doi: 10.1016/j.medj.2022.12.007. Epub 2023 Jan 23. Med. 2023. PMID: 36693381 Free article.
Monitoring melanoma patients on treatment reveals a distinct macrophage population driving targeted therapy resistance.
Vasilevska J, Cheng PF, Lehmann J, Ramelyte E, Gómez JM, Dimitriou F, Sella F; TuPro Consortium; Ferretti D, Salas-Bastos A, Jordaan WS, Levesque MP, Dummer R, Sommer L. Vasilevska J, et al. Among authors: dummer r. Cell Rep Med. 2024 Jul 16;5(7):101611. doi: 10.1016/j.xcrm.2024.101611. Epub 2024 Jun 27. Cell Rep Med. 2024. PMID: 38942020 Free PMC article.
Single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia.
Wegmann R, Bonilla X, Casanova R, Chevrier S, Coelho R, Esposito C, Ficek-Pascual J, Goetze S, Gut G, Jacob F, Jacobs A, Kuipers J, Lischetti U, Mena J, Milani ES, Prummer M, Del Castillo JS, Singer F, Sivapatham S, Toussaint NC, Vilinovszki O, Wildschut MHE, Thavayogarajah T, Malani D; TumorProfiler Consortium; Aebersold R, Bacac M, Beerenwinkel N, Beisel C, Bodenmiller B, Heinzelmann-Schwarz V, Koelzer VH, Levesque MP, Moch H, Pelkmans L, Rätsch G, Tolnay M, Wicki A, Wollscheid B, Manz MG, Snijder B, Theocharides APA. Wegmann R, et al. Nat Commun. 2024 Oct 30;15(1):9402. doi: 10.1038/s41467-024-53535-4. Nat Commun. 2024. PMID: 39477946 Free PMC article.
The genetic evolution of acral melanoma.
Wang M, Fukushima S, Sheen YS, Ramelyte E, Pacheco NC, Shi C, Liu S, Banik I, Aquino JD, Acosta MS, Levesque M, Dummer R, Liau JY, Chu CY, Shain AH, Yeh I, Bastian BC. Wang M, et al. Among authors: dummer r. bioRxiv [Preprint]. 2023 Oct 19:2023.10.18.562802. doi: 10.1101/2023.10.18.562802. bioRxiv. 2023. Update in: Nat Commun. 2024 Jul 21;15(1):6146. doi: 10.1038/s41467-024-50233-z PMID: 37904969 Free PMC article. Updated. Preprint.
1,026 results