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Page 1
Combination therapies of porcupine inhibition with ruxolitinib, ibrutinib or belumosudil in murine sclerodermatous GvHD.
Hong X, Xiao Y, Xu L, Shen L, Neelagar R, Devakumar V, Trinh-Minh T, Liang M, Rius Rigau A, Zhang Y, Li YN, Dees C, Györfi AH, Wolff D, Herr W, Schett G, Distler JHW, Matei AE. Hong X, et al. Among authors: rius rigau a. Blood Adv. 2025 Jan 7:bloodadvances.2024014387. doi: 10.1182/bloodadvances.2024014387. Online ahead of print. Blood Adv. 2025. PMID: 39775728 No abstract available.
Mutual Amplification of GLI2/Hedgehog and Transcription Factor JUN/AP-1 Signaling in Fibroblasts in Systemic Sclerosis: Potential Implications for Combined Therapies.
Bergmann C, Chenguiti Fakhouri S, Trinh-Minh T, Filla T, Rius Rigau A, Ekici AB, Merlevede B, Hallenberger L, Zhu H, Dees C, Matei AE, Auth J, Györfi AH, Zhou X, Rauber S, Bozec A, Dickel N, Liang C, Kunz M, Schett G, Distler JHW. Bergmann C, et al. Among authors: rius rigau a. Arthritis Rheumatol. 2025 Jan;77(1):92-98. doi: 10.1002/art.42979. Epub 2024 Oct 20. Arthritis Rheumatol. 2025. PMID: 39187464 Free PMC article.
CD19-CAR T-cell therapy induces deep tissue depletion of B cells.
Tur C, Eckstein M, Velden J, Rauber S, Bergmann C, Auth J, Bucci L, Corte G, Hagen M, Wirsching A, Grieshaber-Bouyer R, Reis P, Kittan N, Wacker J, Rius Rigau A, Ramming A, D'Agostino MA, Hartmann A, Müller F, Mackensen A, Bozec A, Schett G, Raimondo MG. Tur C, et al. Among authors: rius rigau a. Ann Rheum Dis. 2024 Sep 11:ard-2024-226142. doi: 10.1136/ard-2024-226142. Online ahead of print. Ann Rheum Dis. 2024. PMID: 39153835 Free article.
Combined inhibition of IL-1, IL-33 and IL-36 signalling by targeting IL1RAP ameliorates skin and lung fibrosis in preclinical models of systemic sclerosis.
Grönberg C, Rattik S, Tran-Manh C, Zhou X, Rius Rigau A, Li YN, Györfi AH, Dickel N, Kunz M, Kreuter A, Matei EA, Zhu H, Skoog P, Liberg D, Distler JH, Trinh-Minh T. Grönberg C, et al. Among authors: rius rigau a. Ann Rheum Dis. 2024 Aug 27;83(9):1156-1168. doi: 10.1136/ard-2023-225158. Ann Rheum Dis. 2024. PMID: 38594058 Free PMC article.
Characterization of Vascular Niche in Systemic Sclerosis by Spatial Proteomics.
Rius Rigau A, Li YN, Matei AE, Györfi AH, Bruch PM, Koziel S, Devakumar V, Gabrielli A, Kreuter A, Wang J, Dietrich S, Schett G, Distler JHW, Liang M. Rius Rigau A, et al. Circ Res. 2024 Mar 29;134(7):875-891. doi: 10.1161/CIRCRESAHA.123.323299. Epub 2024 Mar 5. Circ Res. 2024. PMID: 38440901 Free article.
Mouse Models of Skin Fibrosis.
Rius Rigau A, Luber M, Distler JHW. Rius Rigau A, et al. Methods Mol Biol. 2021;2299:371-383. doi: 10.1007/978-1-0716-1382-5_25. Methods Mol Biol. 2021. PMID: 34028755