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Alternative UPS drug targets upstream the 26S proteasome.
Hjerpe R, Rodríguez MS. Hjerpe R, et al. Int J Biochem Cell Biol. 2008;40(6-7):1126-40. doi: 10.1016/j.biocel.2007.11.021. Epub 2007 Dec 8. Int J Biochem Cell Biol. 2008. PMID: 18203645 Review.
Tetramerization-defects of p53 result in aberrant ubiquitylation and transcriptional activity.
Lang V, Pallara C, Zabala A, Lobato-Gil S, Lopitz-Otsoa F, Farrás R, Hjerpe R, Torres-Ramos M, Zabaleta L, Blattner C, Hay RT, Barrio R, Carracedo A, Fernandez-Recio J, Rodríguez MS, Aillet F. Lang V, et al. Among authors: hjerpe r. Mol Oncol. 2014 Jul;8(5):1026-42. doi: 10.1016/j.molonc.2014.04.002. Epub 2014 Apr 13. Mol Oncol. 2014. PMID: 24816189 Free PMC article.
17 results