Chien S - Search Results

1

Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia.

Qin G, Dai J, Chien S, Martins TJ, Loera B, Nguyen QH, Oakes ML, Tercan B, Aguilar B, Hagen L, McCune J, Gelinas R, Monnat RJ Jr, Shmulevich I, Becker PS. Qin G, et al. Among authors: chien s. Clin Cancer Res. 2024 Jun 14;30(12):2659-2671. doi: 10.1158/1078-0432.CCR-23-1674. Clin Cancer Res. 2024. PMID: 38619278 Free PMC article.

2

A machine learning approach to integrate big data for precision medicine in acute myeloid leukemia.

Lee SI, Celik S, Logsdon BA, Lundberg SM, Martins TJ, Oehler VG, Estey EH, Miller CP, Chien S, Dai J, Saxena A, Blau CA, Becker PS. Lee SI, et al. Among authors: chien s. Nat Commun. 2018 Jan 3;9(1):42. doi: 10.1038/s41467-017-02465-5. Nat Commun. 2018. PMID: 29298978 Free PMC article.

3

Unsupervised discovery of dynamic cell phenotypic states from transmitted light movies.

Nguyen P, Chien S, Dai J, Monnat RJ Jr, Becker PS, Kueh HY. Nguyen P, et al. Among authors: chien s. PLoS Comput Biol. 2021 Dec 30;17(12):e1009626. doi: 10.1371/journal.pcbi.1009626. eCollection 2021 Dec. PLoS Comput Biol. 2021. PMID: 34968384 Free PMC article.

4

Case of Chemotherapy-Refractory, RAS-Mutated Chronic Myelomonocytic Leukemia Responsive to Single-Agent Trametinib Based on Results From a High-Throughput Drug Screen.

Halpern AB, Martins TJ, Jonlin EC, Dai J, Chien S, Becker PS. Halpern AB, et al. Among authors: chien s. JCO Precis Oncol. 2020 Nov;4:1367-1373. doi: 10.1200/PO.20.00270. JCO Precis Oncol. 2020. PMID: 35050791 No abstract available.

5

High-Throughput Drug Screening and Multi-Omic Analysis to Guide Individualized Treatment for Multiple Myeloma.

Coffey DG, Cowan AJ, DeGraaff B, Martins TJ, Curley N, Green DJ, Libby EN, Silbermann R, Chien S, Dai J, Morales A, Gooley TA, Warren EH, Becker PS. Coffey DG, et al. Among authors: chien s. JCO Precis Oncol. 2021 Apr 6;5:PO.20.00442. doi: 10.1200/PO.20.00442. eCollection 2021. JCO Precis Oncol. 2021. PMID: 34250400 Free PMC article. Clinical Trial.

6

Accurate detection of subclonal variants in paired diagnosis-relapse acute myeloid leukemia samples by next generation Duplex Sequencing.

Kamath-Loeb AS, Shen JC, Schmitt MW, Kohrn BF, Loeb KR, Estey EH, Dai J, Chien S, Loeb LA, Becker PS. Kamath-Loeb AS, et al. Among authors: chien s. Leuk Res. 2022 Apr;115:106822. doi: 10.1016/j.leukres.2022.106822. Epub 2022 Mar 9. Leuk Res. 2022. PMID: 35303493 Free PMC article.

7

Mesenchymal stromal cells derived from acute myeloid leukemia bone marrow exhibit aberrant cytogenetics and cytokine elaboration.

Huang JC, Basu SK, Zhao X, Chien S, Fang M, Oehler VG, Appelbaum FR, Becker PS. Huang JC, et al. Among authors: chien s. Blood Cancer J. 2015 Apr 10;5(4):e302. doi: 10.1038/bcj.2015.17. Blood Cancer J. 2015. PMID: 25860293 Free PMC article.

8

Very late antigen-4 function of myeloblasts correlates with improved overall survival for patients with acute myeloid leukemia.

Becker PS, Kopecky KJ, Wilks AN, Chien S, Harlan JM, Willman CL, Petersdorf SH, Stirewalt DL, Papayannopoulou T, Appelbaum FR. Becker PS, et al. Among authors: chien s. Blood. 2009 Jan 22;113(4):866-74. doi: 10.1182/blood-2007-12-124818. Epub 2008 Oct 16. Blood. 2009. PMID: 18927435 Free PMC article.

9

Restoring RUNX1 deficiency in RUNX1 familial platelet disorder by inhibiting its degradation.

Krutein MC, Hart MR, Anderson DJ, Jeffery J, Kotini AG, Dai J, Chien S, DelPriore M, Borst S, Maguire JA, French DL, Gadue P, Papapetrou EP, Keel SB, Becker PS, Horwitz MS. Krutein MC, et al. Among authors: chien s. Blood Adv. 2021 Feb 9;5(3):687-699. doi: 10.1182/bloodadvances.2020002709. Blood Adv. 2021. PMID: 33560381 Free PMC article.

10

Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector.

Becker PS, Taylor JA, Trobridge GD, Zhao X, Beard BC, Chien S, Adair J, Kohn DB, Wagner JE, Shimamura A, Kiem HP. Becker PS, et al. Among authors: chien s. Gene Ther. 2010 Oct;17(10):1244-52. doi: 10.1038/gt.2010.62. Epub 2010 May 20. Gene Ther. 2010. PMID: 20485382 Free PMC article.

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