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Page 1
Exposing the molecular heterogeneity of glycosylated biotherapeutics.
Schachner LF, Mullen C, Phung W, Hinkle JD, Beardsley MI, Bentley T, Day P, Tsai C, Sukumaran S, Baginski T, DiCara D, Agard NJ, Masureel M, Gober J, ElSohly AM, Melani R, Syka JEP, Huguet R, Marty MT, Sandoval W. Schachner LF, et al. Among authors: masureel m. Nat Commun. 2024 Apr 16;15(1):3259. doi: 10.1038/s41467-024-47693-8. Nat Commun. 2024. PMID: 38627419 Free PMC article.
Multiparametric Single-Vesicle Flow Cytometry Resolves Extracellular Vesicle Heterogeneity and Reveals Selective Regulation of Biogenesis and Cargo Distribution.
von Lersner AK, Fernandes F, Ozawa PMM, Jackson M, Masureel M, Ho H, Lima SM, Vagner T, Sung BH, Wehbe M, Franze K, Pua H, Wilson JT, Irish JM, Weaver AM, Di Vizio D, Zijlstra A. von Lersner AK, et al. Among authors: masureel m. ACS Nano. 2024 Apr 16;18(15):10464-10484. doi: 10.1021/acsnano.3c11561. Epub 2024 Apr 5. ACS Nano. 2024. PMID: 38578701 Free PMC article.
Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation.
Dorel R, Sun D, Carruthers N, Castanedo GM, Ung PM, Factor DC, Li T, Baumann H, Janota D, Pang J, Salphati L, Meklemburg R, Korman AJ, Harper HE, Stubblefield S, Payandeh J, McHugh D, Lang BT, Tesar PJ, Dere E, Masureel M, Adams DJ, Volgraf M, Braun MG. Dorel R, et al. Among authors: masureel m. J Med Chem. 2024 Mar 28;67(6):4819-4832. doi: 10.1021/acs.jmedchem.3c02396. Epub 2024 Mar 12. J Med Chem. 2024. PMID: 38470227
Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Liang WC, Xi H, Sun D, D'Ascenzo L, Zarzar J, Stephens N, Cook R, Li Y, Ye Z, Matsumoto M, Payandeh J, Masureel M, Wu Y. Liang WC, et al. Among authors: masureel m. MAbs. 2024 Jan-Dec;16(1):2309685. doi: 10.1080/19420862.2024.2309685. Epub 2024 Feb 14. MAbs. 2024. PMID: 38356181 Free PMC article.
Toxigenic Clostridium perfringens Isolated from At-Risk Paediatric Inflammatory Bowel Disease Patients.
Kuo J, Uzunovic J, Jacobson A, Dourado M, Gierke S, Rajendram M, Keilberg D, Mar J, Stekol E, Curry J, Verstraete S, Lund J, Liang Y, Tamburini FB, Omattage NS, Masureel M, Rutherford ST, Hackos DH, Tan MW, Byrd AL, Keir ME, Skippington E, Storek KM. Kuo J, et al. Among authors: masureel m. J Crohns Colitis. 2024 Aug 6;18(7):985-1001. doi: 10.1093/ecco-jcc/jjae016. J Crohns Colitis. 2024. PMID: 38267224 Free PMC article.
Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Sun D, Sun Y, Janezic E, Zhou T, Johnson M, Azumaya C, Noreng S, Chiu C, Seki A, Arenzana TL, Nicoludis JM, Shi Y, Wang B, Ho H, Joshi P, Tam C, Payandeh J, Comps-Agrar L, Wang J, Rutz S, Koerber JT, Masureel M. Sun D, et al. Among authors: masureel m. Nat Commun. 2023 Dec 1;14(1):7940. doi: 10.1038/s41467-023-43601-8. Nat Commun. 2023. PMID: 38040762 Free PMC article.
Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics.
Janetzko J, Kise R, Barsi-Rhyne B, Siepe DH, Heydenreich FM, Kawakami K, Masureel M, Maeda S, Garcia KC, von Zastrow M, Inoue A, Kobilka BK. Janetzko J, et al. Among authors: masureel m. Cell. 2022 Nov 23;185(24):4560-4573.e19. doi: 10.1016/j.cell.2022.10.018. Epub 2022 Nov 10. Cell. 2022. PMID: 36368322 Free PMC article.
Structure of the core human NADPH oxidase NOX2.
Noreng S, Ota N, Sun Y, Ho H, Johnson M, Arthur CP, Schneider K, Lehoux I, Davies CW, Mortara K, Wong K, Seshasayee D, Masureel M, Payandeh J, Yi T, Koerber JT. Noreng S, et al. Among authors: masureel m. Nat Commun. 2022 Oct 14;13(1):6079. doi: 10.1038/s41467-022-33711-0. Nat Commun. 2022. PMID: 36241643 Free PMC article.
How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling.
Latorraca NR, Masureel M, Hollingsworth SA, Heydenreich FM, Suomivuori CM, Brinton C, Townshend RJL, Bouvier M, Kobilka BK, Dror RO. Latorraca NR, et al. Among authors: masureel m. Cell. 2020 Dec 23;183(7):1813-1825.e18. doi: 10.1016/j.cell.2020.11.014. Epub 2020 Dec 8. Cell. 2020. PMID: 33296703 Free PMC article.
25 results